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Reactivation of telomerase reverse transcriptase expression in cancer: the role of TERT promoter mutations
Telomerase activity and telomere elongation are essential conditions for the unlimited proliferation of neoplastic cells. Point mutations in the core promoter region of the telomerase reverse transcriptase (TERT) gene have been found to occur at high frequencies in several tumour types and considere...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684755/ https://www.ncbi.nlm.nih.gov/pubmed/38033865 http://dx.doi.org/10.3389/fcell.2023.1286683 |