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Prediction of histone deacetylase inhibition by triazole compounds based on artificial intelligence
A quantitative structure-activity relationship (QSAR) study was conducted to predict the anti-colon cancer and HDAC inhibition of triazole-containing compounds. Four descriptors were selected from 579 descriptors which have the most obvious effect on the inhibition of histone deacetylase (HDAC). Fou...
Autores principales: | Wang, Yiran, Zhang, Peijian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684768/ https://www.ncbi.nlm.nih.gov/pubmed/38035010 http://dx.doi.org/10.3389/fphar.2023.1260349 |
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