Single cell and spatial transcriptomics analysis of kidney double negative T lymphocytes in normal and ischemic mouse kidneys

T cells are important in the pathogenesis of acute kidney injury (AKI), and TCR(+)CD4(-)CD8(-) (double negative-DN) are T cells that have regulatory properties. However, there is limited information on DN T cells compared to traditional CD4(+) and CD8(+) cells. To elucidate the molecular signature a...

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Detalles Bibliográficos
Autores principales: Gharaie, Sepideh, Lee, Kyungho, Noller, Kathleen, Lo, Emily K., Miller, Brendan, Jung, Hyun Jun, Newman-Rivera, Andrea M., Kurzhagen, Johanna T., Singla, Nirmish, Welling, Paul A., Fan, Jean, Cahan, Patrick, Noel, Sanjeev, Rabb, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684868/
https://www.ncbi.nlm.nih.gov/pubmed/38017015
http://dx.doi.org/10.1038/s41598-023-48213-2

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