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Generation of “OP7 chimera” defective interfering influenza A particle preparations free of infectious virus that show antiviral efficacy in mice

Influenza A virus (IAV) defective interfering particles (DIPs) are considered as new promising antiviral agents. Conventional DIPs (cDIPs) contain a deletion in the genome and can only replicate upon co-infection with infectious standard virus (STV), during which they suppress STV replication. We pr...

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Detalles Bibliográficos
Autores principales: Dogra, Tanya, Pelz, Lars, Boehme, Julia D., Kuechler, Jan, Kershaw, Olivia, Marichal-Gallardo, Pavel, Baelkner, Maike, Hein, Marc D., Gruber, Achim D., Benndorf, Dirk, Genzel, Yvonne, Bruder, Dunja, Kupke, Sascha Y., Reichl, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684881/
https://www.ncbi.nlm.nih.gov/pubmed/38017026
http://dx.doi.org/10.1038/s41598-023-47547-1