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Generation of “OP7 chimera” defective interfering influenza A particle preparations free of infectious virus that show antiviral efficacy in mice
Influenza A virus (IAV) defective interfering particles (DIPs) are considered as new promising antiviral agents. Conventional DIPs (cDIPs) contain a deletion in the genome and can only replicate upon co-infection with infectious standard virus (STV), during which they suppress STV replication. We pr...
Autores principales: | Dogra, Tanya, Pelz, Lars, Boehme, Julia D., Kuechler, Jan, Kershaw, Olivia, Marichal-Gallardo, Pavel, Baelkner, Maike, Hein, Marc D., Gruber, Achim D., Benndorf, Dirk, Genzel, Yvonne, Bruder, Dunja, Kupke, Sascha Y., Reichl, Udo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684881/ https://www.ncbi.nlm.nih.gov/pubmed/38017026 http://dx.doi.org/10.1038/s41598-023-47547-1 |
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