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INPP5D regulates inflammasome activation in human microglia
Microglia and neuroinflammation play an important role in the development and progression of Alzheimer’s disease (AD). Inositol polyphosphate-5-phosphatase D (INPP5D/SHIP1) is a myeloid-expressed gene genetically-associated with AD. Through unbiased analyses of RNA and protein profiles in INPP5D-dis...
Autores principales: | Chou, Vicky, Pearse, Richard V., Aylward, Aimee J., Ashour, Nancy, Taga, Mariko, Terzioglu, Gizem, Fujita, Masashi, Fancher, Seeley B., Sigalov, Alina, Benoit, Courtney R., Lee, Hyo, Lam, Matti, Seyfried, Nicholas T., Bennett, David A., De Jager, Philip L., Menon, Vilas, Young-Pearse, Tracy L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684891/ https://www.ncbi.nlm.nih.gov/pubmed/38016942 http://dx.doi.org/10.1038/s41467-023-42819-w |
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