Cargando…

Treatment of Chronic Constipation using Elobixibat in a Real-World Setting: A Retrospective Cohort Study using an Electronic Medical Records Database in Japan

BACKGROUND: Chronic constipation is a common condition affecting people of all ages; therefore, the socioeconomic burden of chronic constipation is nonnegligible. Elobixibat (ELO), an ileal bail acid transport inhibitor, was launched in Japan in 2018. However, evidence of its use in diverse populati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Masaki, Hisanori, Shimamoto, Koji, Inokuchi, Shoichiro, Ishizaki, Sonoko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685011/ https://www.ncbi.nlm.nih.gov/pubmed/38033932 http://dx.doi.org/10.1016/j.curtheres.2023.100724

Ejemplares similares

Impact of elobixibat on serum and fecal bile acid levels and constipation symptoms in patients with chronic constipation
por: Nakajima, Atsushi, et al.
Publicado: (2022)

Effects of Elobixibat in Patients with Diabetes and Concomitant Chronic Constipation: an 8-week, Prospective, Single-center, Single-arm Study
por: Hishida, Yoshiaki, et al.
Publicado: (2022)

Elobixibat improves rectal sensation in patients with chronic constipation aged ≥60 years: a randomised placebo-controlled study
por: Manabe, Noriaki, et al.
Publicado: (2023)

Elobixibat alleviates chronic constipation in hemodialysis patients: a questionnaire-based study
por: Kamei, Daigo, et al.
Publicado: (2020)

The Efficacy and Safety of Elobixibat for the Elderly with Chronic Constipation: A Multicenter Retrospective Cohort Study
por: Tomie, Akira, et al.
Publicado: (2020)

Elobixibat Effectively Relieves Chronic Constipation in Patients with Cancer Regardless of the Amount of Food Intake
por: Ozaki, Anna, et al.
Publicado: (2021)

Efficacy and Safety of Elobixibat in Elderly Patients with Chronic Constipation: A Single-center, Observational Study
por: Abe, Tatsuya, et al.
Publicado: (2020)

Effects of Elobixibat on Constipation and Lipid Metabolism in Patients With Moderate to End-Stage Chronic Kidney Disease
por: Matsuyama, Momoko, et al.
Publicado: (2022)

Correction to: Elobixibat Effectively Relieves Chronic Constipation in Patients with Cancer Regardless of the Amount of Food Intake
Publicado: (2023)

Efficacy, long‐term safety, and impact on quality of life of elobixibat in more severe constipation: Post hoc analyses of two phase 3 trials in Japan
por: Nakajima, Atsushi, et al.
Publicado: (2019)

Uncontrolled, Open-Label Pre-Dinner Administration of Elobixibat in Japanese Adults with Chronic Constipation: A Retrospective Chart Review
por: Odaka, Takeo, et al.
Publicado: (2020)

Effect of single and multiple doses of elobixibat, an ileal bile acid transporter inhibitor, on chronic constipation: A randomized controlled trial
por: Kumagai, Yuji, et al.
Publicado: (2018)

Rationale and design of a multicenter, single-group, open-label trial aiming at investigating the effectiveness of elobixibat for loss of defecation desire in patients with chronic constipation
por: Yamamoto, Atsushi, et al.
Publicado: (2022)

Safety and Efficacy of Elobixibat, an Ileal Bile Acid Transporter Inhibitor, in Elderly Patients With Chronic Idiopathic Constipation According to Administration Time: Interim Analysis of Post-marketing Surveillance
por: Nakajima, Atsushi, et al.
Publicado: (2022)

Rationale and design of a multicentre, 12-week, randomised, double-blind, placebo-controlled, parallel-group, investigator-initiated trial to investigate the efficacy and safety of elobixibat for chronic constipation
por: Tanaka, Kosuke, et al.
Publicado: (2022)

Association between radicular low back pain and constipation: a retrospective cohort study using a real-world national database
por: Trager, Robert James, et al.
Publicado: (2021)

A Nationwide Hospital Claims Database Analysis of Real-World Patterns of Laxative Use for Opioid-Induced Constipation in Japanese Patients with Cancer
por: Higashibata, Takahiro, et al.
Publicado: (2023)

Efficacy of elobixibat as bowel preparation agent for colonoscopy: Prospective, randomized, multi‐center study
por: Yamaguchi, Daisuke, et al.
Publicado: (2021)

Real World Treatment Practices for Mantle Cell Lymphoma in Japan: An Observational Database Research Study (CLIMBER-DBR)
por: Izutsu, Koji, et al.
Publicado: (2021)

Real World Treatment Practices for Chronic Lymphocytic Leukemia in Japan: An Observational Database Research Study (CLIMBER-DBR)
por: Takizawa, Jun, et al.
Publicado: (2021)

Real-world evidence of trifluridine/tipiracil plus bevacizumab in metastatic colorectal cancer using an administrative claims database in Japan
por: Kagawa, Y., et al.
Publicado: (2023)

Investigating the efficacy and safety of elobixibat, an ileal bile acid transporter inhibitor, in patients with Parkinson’s disease with chronic constipation: a multicentre, placebo-controlled, randomised, double-blind, parallel-group study (CONST-PD)
por: Hatano, Taku, et al.
Publicado: (2022)

Tracheostomy decannulation rates in Japan: a retrospective cohort study using a claims database
por: Ishizaki, Miho, et al.
Publicado: (2022)

From real-world electronic health record data to real-world results using artificial intelligence
por: Knevel, Rachel, et al.
Publicado: (2023)

Determining an optimal clinical dose of elobixibat, a novel inhibitor of the ileal bile acid transporter, in Japanese patients with chronic constipation: a phase II, multicenter, double-blind, placebo-controlled randomized clinical trial
por: Nakajima, Atsushi, et al.
Publicado: (2017)

Effectiveness of mepolizumab in severe asthma in Japan: A real‐world study using claims data
por: Nagase, Hiroyuki, et al.
Publicado: (2021)

A retrospective, cross-sectional study of real-world values of cardiovascular risk factors using a healthcare database in Japan
por: Shima, Daisuke, et al.
Publicado: (2014)

Context and Considerations for Use of Two Japanese Real-World Databases in Japan: Medical Data Vision and Japanese Medical Data Center
por: Laurent, Thomas, et al.
Publicado: (2022)

Clinical epidemiology and pharmacoepidemiology studies with real-world databases
por: YOSHIDA, Satomi, et al.
Publicado: (2022)

Real‐world burden and treatment of chronic rhinosinusitis in Japan: A retrospective claims database analysis
por: Yoshikawa, Mamoru, et al.
Publicado: (2023)

Translation and Validation Testing of the Constipation-Related Quality of Life Scale for Use in Japan
por: Hamaguchi, Sugihiro, et al.
Publicado: (2023)

Real-World Epidemiology, Clinical and Economic Burden of Chronic Hepatitis B in Japan: A Retrospective Study Using JMDC Claims Database
por: Umemura, Takeji, et al.
Publicado: (2023)

Combined, elobixibat, and colestyramine reduced cholesterol toxicity in a mouse model of metabolic dysfunction-associated steatotic liver disease
por: Iwaki, Michihiro, et al.
Publicado: (2023)

A novel digital approach to describe real world outcomes among patients with constipation
por: Shapiro, Allison, et al.
Publicado: (2021)

Evaluation of advanced techniques for multi-party privacy-preserving record linkage on real-world health databases
por: Ranbaduge, Thilina, et al.
Publicado: (2017)

Cerner real-world data (CRWD) - A de-identified multicenter electronic health records database
por: Ehwerhemuepha, Louis, et al.
Publicado: (2022)

A questionnaire-based survey on the etiopathogenesis of chronic constipation during a medical check-up in Japan
por: Otani, Koji, et al.
Publicado: (2022)

Persistence rates and medical costs of biological therapies for psoriasis treatment in Japan: a real-world data study using a claims database
por: Sruamsiri, Rosarin, et al.
Publicado: (2018)

Comparing record linkage software programs and algorithms using real-world data
por: Karr, Alan F., et al.
Publicado: (2019)

Comparative Study of Constipation Exacerbation by Potassium Binders Using a Loperamide-Induced Constipation Model
por: Narita, Yuki, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_j4idjkpq9a0iq58f0ceh2snet4