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Mechanisms by which microbial enzymes degrade four mycotoxins and application in animal production: A review

Mycotoxins are toxic compounds that pose a serious threat to animal health and food safety. Therefore, there is an urgent need for safe and efficient methods of detoxifying mycotoxins. As biotechnology has continued to develop, methods involving biological enzymes have shown great promise. Biologica...

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Detalles Bibliográficos
Autores principales: Sun, Huiying, He, Ziqi, Xiong, Dongwei, Long, Miao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685049/
https://www.ncbi.nlm.nih.gov/pubmed/38033608
http://dx.doi.org/10.1016/j.aninu.2023.09.003
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author Sun, Huiying
He, Ziqi
Xiong, Dongwei
Long, Miao
author_facet Sun, Huiying
He, Ziqi
Xiong, Dongwei
Long, Miao
author_sort Sun, Huiying
collection PubMed
description Mycotoxins are toxic compounds that pose a serious threat to animal health and food safety. Therefore, there is an urgent need for safe and efficient methods of detoxifying mycotoxins. As biotechnology has continued to develop, methods involving biological enzymes have shown great promise. Biological enzymatic methods, which can fundamentally destroy the structures of mycotoxins and produce degradation products whose toxicity is greatly reduced, are generally more specific, efficient, and environmentally friendly. Mycotoxin-degrading enzymes can thus facilitate the safe and effective detoxification of mycotoxins which gives them a huge advantage over other methods. This article summarizes the newly discovered degrading enzymes that can degrade four common mycotoxins (aflatoxins, zearalenone, deoxynivalenol, and ochratoxin A) in the past five years, and reveals the degradation mechanism of degrading enzymes on four mycotoxins, as well as their positive effects on animal production. This review will provide a theoretical basis for the safe treatment of mycotoxins by using biological enzyme technology.
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spelling pubmed-106850492023-11-30 Mechanisms by which microbial enzymes degrade four mycotoxins and application in animal production: A review Sun, Huiying He, Ziqi Xiong, Dongwei Long, Miao Anim Nutr Review Article Mycotoxins are toxic compounds that pose a serious threat to animal health and food safety. Therefore, there is an urgent need for safe and efficient methods of detoxifying mycotoxins. As biotechnology has continued to develop, methods involving biological enzymes have shown great promise. Biological enzymatic methods, which can fundamentally destroy the structures of mycotoxins and produce degradation products whose toxicity is greatly reduced, are generally more specific, efficient, and environmentally friendly. Mycotoxin-degrading enzymes can thus facilitate the safe and effective detoxification of mycotoxins which gives them a huge advantage over other methods. This article summarizes the newly discovered degrading enzymes that can degrade four common mycotoxins (aflatoxins, zearalenone, deoxynivalenol, and ochratoxin A) in the past five years, and reveals the degradation mechanism of degrading enzymes on four mycotoxins, as well as their positive effects on animal production. This review will provide a theoretical basis for the safe treatment of mycotoxins by using biological enzyme technology. KeAi Publishing 2023-10-04 /pmc/articles/PMC10685049/ /pubmed/38033608 http://dx.doi.org/10.1016/j.aninu.2023.09.003 Text en © 2023 The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review Article
Sun, Huiying
He, Ziqi
Xiong, Dongwei
Long, Miao
Mechanisms by which microbial enzymes degrade four mycotoxins and application in animal production: A review
title Mechanisms by which microbial enzymes degrade four mycotoxins and application in animal production: A review
title_full Mechanisms by which microbial enzymes degrade four mycotoxins and application in animal production: A review
title_fullStr Mechanisms by which microbial enzymes degrade four mycotoxins and application in animal production: A review
title_full_unstemmed Mechanisms by which microbial enzymes degrade four mycotoxins and application in animal production: A review
title_short Mechanisms by which microbial enzymes degrade four mycotoxins and application in animal production: A review
title_sort mechanisms by which microbial enzymes degrade four mycotoxins and application in animal production: a review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685049/
https://www.ncbi.nlm.nih.gov/pubmed/38033608
http://dx.doi.org/10.1016/j.aninu.2023.09.003
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