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Mechanisms by which microbial enzymes degrade four mycotoxins and application in animal production: A review
Mycotoxins are toxic compounds that pose a serious threat to animal health and food safety. Therefore, there is an urgent need for safe and efficient methods of detoxifying mycotoxins. As biotechnology has continued to develop, methods involving biological enzymes have shown great promise. Biologica...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685049/ https://www.ncbi.nlm.nih.gov/pubmed/38033608 http://dx.doi.org/10.1016/j.aninu.2023.09.003 |
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author | Sun, Huiying He, Ziqi Xiong, Dongwei Long, Miao |
author_facet | Sun, Huiying He, Ziqi Xiong, Dongwei Long, Miao |
author_sort | Sun, Huiying |
collection | PubMed |
description | Mycotoxins are toxic compounds that pose a serious threat to animal health and food safety. Therefore, there is an urgent need for safe and efficient methods of detoxifying mycotoxins. As biotechnology has continued to develop, methods involving biological enzymes have shown great promise. Biological enzymatic methods, which can fundamentally destroy the structures of mycotoxins and produce degradation products whose toxicity is greatly reduced, are generally more specific, efficient, and environmentally friendly. Mycotoxin-degrading enzymes can thus facilitate the safe and effective detoxification of mycotoxins which gives them a huge advantage over other methods. This article summarizes the newly discovered degrading enzymes that can degrade four common mycotoxins (aflatoxins, zearalenone, deoxynivalenol, and ochratoxin A) in the past five years, and reveals the degradation mechanism of degrading enzymes on four mycotoxins, as well as their positive effects on animal production. This review will provide a theoretical basis for the safe treatment of mycotoxins by using biological enzyme technology. |
format | Online Article Text |
id | pubmed-10685049 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | KeAi Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-106850492023-11-30 Mechanisms by which microbial enzymes degrade four mycotoxins and application in animal production: A review Sun, Huiying He, Ziqi Xiong, Dongwei Long, Miao Anim Nutr Review Article Mycotoxins are toxic compounds that pose a serious threat to animal health and food safety. Therefore, there is an urgent need for safe and efficient methods of detoxifying mycotoxins. As biotechnology has continued to develop, methods involving biological enzymes have shown great promise. Biological enzymatic methods, which can fundamentally destroy the structures of mycotoxins and produce degradation products whose toxicity is greatly reduced, are generally more specific, efficient, and environmentally friendly. Mycotoxin-degrading enzymes can thus facilitate the safe and effective detoxification of mycotoxins which gives them a huge advantage over other methods. This article summarizes the newly discovered degrading enzymes that can degrade four common mycotoxins (aflatoxins, zearalenone, deoxynivalenol, and ochratoxin A) in the past five years, and reveals the degradation mechanism of degrading enzymes on four mycotoxins, as well as their positive effects on animal production. This review will provide a theoretical basis for the safe treatment of mycotoxins by using biological enzyme technology. KeAi Publishing 2023-10-04 /pmc/articles/PMC10685049/ /pubmed/38033608 http://dx.doi.org/10.1016/j.aninu.2023.09.003 Text en © 2023 The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Article Sun, Huiying He, Ziqi Xiong, Dongwei Long, Miao Mechanisms by which microbial enzymes degrade four mycotoxins and application in animal production: A review |
title | Mechanisms by which microbial enzymes degrade four mycotoxins and application in animal production: A review |
title_full | Mechanisms by which microbial enzymes degrade four mycotoxins and application in animal production: A review |
title_fullStr | Mechanisms by which microbial enzymes degrade four mycotoxins and application in animal production: A review |
title_full_unstemmed | Mechanisms by which microbial enzymes degrade four mycotoxins and application in animal production: A review |
title_short | Mechanisms by which microbial enzymes degrade four mycotoxins and application in animal production: A review |
title_sort | mechanisms by which microbial enzymes degrade four mycotoxins and application in animal production: a review |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685049/ https://www.ncbi.nlm.nih.gov/pubmed/38033608 http://dx.doi.org/10.1016/j.aninu.2023.09.003 |
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