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Effects of glycine 64 substitutions in RNA-dependent RNA polymerase on ribavirin sensitivity and pathogenicity of coxsackievirus A6

Hand, foot, and mouth disease (HFMD) caused by a group of enteroviruses is a global public health problem. In recent years, coxsackievirus A6 (CVA6) has emerged as an important HFMD agent. Previous studies have shown that mutations of glycine 64 in RNA-dependent RNA polymerase (3D polymerase), which...

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Detalles Bibliográficos
Autores principales: Wang, Rui, Sun, Qiang, Xiao, Jinbo, Wang, Congcong, Li, Xiaoliang, Li, Jichen, Song, Yang, Lu, Huanhuan, Liu, Ying, Zhu, Shuangli, Liu, Zhijun, Zhang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685073/
https://www.ncbi.nlm.nih.gov/pubmed/37949376
http://dx.doi.org/10.1016/j.virusres.2023.199268