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New-Onset Graves’ Disease With Thyroid Storm After COVID-19 Infection

COVID-19 has been a known cause of triggering autoimmune conditions. Previous literature demonstrates an increase in the incidence of Graves’ disease during the COVID-19 pandemic. The virus is thought to affect genetics, leading to a cascade of events that cause hyperthyroidism. In our case, an 81-y...

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Detalles Bibliográficos
Autores principales: Shermetaro, Angela, Bushman, Jordan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685078/
https://www.ncbi.nlm.nih.gov/pubmed/38034228
http://dx.doi.org/10.7759/cureus.47995
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author Shermetaro, Angela
Bushman, Jordan
author_facet Shermetaro, Angela
Bushman, Jordan
author_sort Shermetaro, Angela
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description COVID-19 has been a known cause of triggering autoimmune conditions. Previous literature demonstrates an increase in the incidence of Graves’ disease during the COVID-19 pandemic. The virus is thought to affect genetics, leading to a cascade of events that cause hyperthyroidism. In our case, an 81-year-old male presented with symptoms of palpitations, tremors, dizziness, diarrhea, and fatigue. He was found to be in atrial fibrillation with rapid ventricular response, and his workup was consistent with hyperthyroidism. Based on his Burch-Wartofsky score, the diagnosis of thyroid storm was made. There are a limited number of case reports with new-onset Graves’ disease after COVID-19 infection. Interestingly, our patient was also in a thyroid storm. He was treated with hydrocortisone cholestyramine, potassium, and propylthiouracil. After treatment, his symptoms resolved, and his thyroid studies improved. We chose to present this case because it demonstrates one of the many autoimmune effects that COVID-19 has been linked to.
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spelling pubmed-106850782023-11-30 New-Onset Graves’ Disease With Thyroid Storm After COVID-19 Infection Shermetaro, Angela Bushman, Jordan Cureus Endocrinology/Diabetes/Metabolism COVID-19 has been a known cause of triggering autoimmune conditions. Previous literature demonstrates an increase in the incidence of Graves’ disease during the COVID-19 pandemic. The virus is thought to affect genetics, leading to a cascade of events that cause hyperthyroidism. In our case, an 81-year-old male presented with symptoms of palpitations, tremors, dizziness, diarrhea, and fatigue. He was found to be in atrial fibrillation with rapid ventricular response, and his workup was consistent with hyperthyroidism. Based on his Burch-Wartofsky score, the diagnosis of thyroid storm was made. There are a limited number of case reports with new-onset Graves’ disease after COVID-19 infection. Interestingly, our patient was also in a thyroid storm. He was treated with hydrocortisone cholestyramine, potassium, and propylthiouracil. After treatment, his symptoms resolved, and his thyroid studies improved. We chose to present this case because it demonstrates one of the many autoimmune effects that COVID-19 has been linked to. Cureus 2023-10-30 /pmc/articles/PMC10685078/ /pubmed/38034228 http://dx.doi.org/10.7759/cureus.47995 Text en Copyright © 2023, Shermetaro et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Shermetaro, Angela
Bushman, Jordan
New-Onset Graves’ Disease With Thyroid Storm After COVID-19 Infection
title New-Onset Graves’ Disease With Thyroid Storm After COVID-19 Infection
title_full New-Onset Graves’ Disease With Thyroid Storm After COVID-19 Infection
title_fullStr New-Onset Graves’ Disease With Thyroid Storm After COVID-19 Infection
title_full_unstemmed New-Onset Graves’ Disease With Thyroid Storm After COVID-19 Infection
title_short New-Onset Graves’ Disease With Thyroid Storm After COVID-19 Infection
title_sort new-onset graves’ disease with thyroid storm after covid-19 infection
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685078/
https://www.ncbi.nlm.nih.gov/pubmed/38034228
http://dx.doi.org/10.7759/cureus.47995
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