New discoveries on how DICER efficiently processes pre‐miRNA

The latest study identified the “GYM motif” on precursor microRNA (pre‐miRNA) for the first time and highlighted its key role in DICER specifically recognizing and efficiently cleaving pre‐miRNA to produce miRNA. In addition, the dicing state of DICER efficiently processing pre‐miRNA was revealed, w...

Descripción completa

Detalles Bibliográficos
Autores principales: Weng, Qi, Wu, Qi, Zheng, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Highlights
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685087/
https://www.ncbi.nlm.nih.gov/pubmed/38034100
http://dx.doi.org/10.1002/mco2.430
_version_ 1785151552921534464
author Weng, Qi
Wu, Qi
Zheng, Quan
author_facet Weng, Qi
Wu, Qi
Zheng, Quan
author_sort Weng, Qi
collection PubMed
description The latest study identified the “GYM motif” on precursor microRNA (pre‐miRNA) for the first time and highlighted its key role in DICER specifically recognizing and efficiently cleaving pre‐miRNA to produce miRNA. In addition, the dicing state of DICER efficiently processing pre‐miRNA was revealed, which was previously difficult to capture. [Image: see text]
format Online
Article
Text
id pubmed-10685087
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-106850872023-11-30 New discoveries on how DICER efficiently processes pre‐miRNA Weng, Qi Wu, Qi Zheng, Quan MedComm (2020) Highlights The latest study identified the “GYM motif” on precursor microRNA (pre‐miRNA) for the first time and highlighted its key role in DICER specifically recognizing and efficiently cleaving pre‐miRNA to produce miRNA. In addition, the dicing state of DICER efficiently processing pre‐miRNA was revealed, which was previously difficult to capture. [Image: see text] John Wiley and Sons Inc. 2023-11-29 /pmc/articles/PMC10685087/ /pubmed/38034100 http://dx.doi.org/10.1002/mco2.430 Text en © 2023 The Authors. MedComm published by Sichuan International Medical Exchange & Promotion Association (SCIMEA) and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Highlights
Weng, Qi
Wu, Qi
Zheng, Quan
New discoveries on how DICER efficiently processes pre‐miRNA
title New discoveries on how DICER efficiently processes pre‐miRNA
title_full New discoveries on how DICER efficiently processes pre‐miRNA
title_fullStr New discoveries on how DICER efficiently processes pre‐miRNA
title_full_unstemmed New discoveries on how DICER efficiently processes pre‐miRNA
title_short New discoveries on how DICER efficiently processes pre‐miRNA
title_sort new discoveries on how dicer efficiently processes pre‐mirna
topic Highlights
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685087/
https://www.ncbi.nlm.nih.gov/pubmed/38034100
http://dx.doi.org/10.1002/mco2.430
work_keys_str_mv AT wengqi newdiscoveriesonhowdicerefficientlyprocessespremirna
AT wuqi newdiscoveriesonhowdicerefficientlyprocessespremirna
AT zhengquan newdiscoveriesonhowdicerefficientlyprocessespremirna

Ejemplares similares