SIRT1 Controls Enteroendocrine Progenitor Cell Proliferation in High-Fat Diet-Fed Mice

BACKGROUND & AIMS: We aimed to investigate how sirtuin 1 (SIRT1), a conserved mammalian Nicotinamide adenine dinucleotide(+)-dependent protein deacetylase, regulates the number of enteroendocrine cells (EECs). EECs benefit metabolism, and their increase potentially could treat type 2 diabetes an...

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Detalles Bibliográficos
Autores principales: Miura, Masaomi, Igarashi, Masaki, Isotani, Ryosuke, Nakagawa-Nagahama, Yoshiko, Kuranami, Satoshi, Naruse, Kyoko, Kadowaki, Takashi, Yamauchi, Toshimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685171/
https://www.ncbi.nlm.nih.gov/pubmed/37598893
http://dx.doi.org/10.1016/j.jcmgh.2023.08.006

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