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One-pot synthesis of pyrazolo[4,3-d]thiazole derivatives containing α-aminophosphonate as potential Mur A inhibitors against MDR pathogens with radiosterilization and molecular modeling simulation

The present study involves the synthesis of a new series of α-aminophosphonate derivatives in good yields with a simple workup via the Kabachnik–Fields reaction using lithium perchlorate (LiClO(4)) as a catalyst to facilitate the reaction. All the newly synthesized compounds were confirmed using var...

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Detalles Bibliográficos
Autores principales: Ragab, Ahmed, Ibrahim, Seham A., Aboul-Magd, Dina S., Baren, Mohamed H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685179/
https://www.ncbi.nlm.nih.gov/pubmed/38035237
http://dx.doi.org/10.1039/d3ra07040a

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