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Mannan-binding lectin ameliorates renal fibrosis by suppressing macrophage-to-myofibroblast transition

Mannan-binding lectin (MBL) is a pattern-recognition molecule that plays a crucial role in innate immunity. MBL deficiency correlates with an increased risk of chronic kidney disease (CKD). However, the molecular mechanisms are not fully defined. Here, we established a CKD model in wild-type (WT) an...

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Detalles Bibliográficos
Autores principales:	Xu, Li, Jiang, Honglian, Xie, Jingwen, Xu, Qishan, Zhou, Jia, Lu, Xiao, Wang, Mingyong, Dong, Lijun, Zuo, Daming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685189/ https://www.ncbi.nlm.nih.gov/pubmed/38034794 http://dx.doi.org/10.1016/j.heliyon.2023.e21882

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