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Solid-state NMR chemical shift analysis for determining the conformation of ATP bound to Na,K-ATPase in its native membrane

Structures of membrane proteins determined by X-ray crystallography and, increasingly, by cryo-electron microscopy often fail to resolve the structural details of unstable or reactive small molecular ligands in their physiological sites. This work demonstrates that (13)C chemical shifts measured by...

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Detalles Bibliográficos
Autores principales:	Middleton, David A., Griffin, John, Esmann, Mikael, Fedosova, Natalya U.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685339/ https://www.ncbi.nlm.nih.gov/pubmed/38035247 http://dx.doi.org/10.1039/d3ra06236h

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