Exploiting Substrate Specificities of 6-O-Sulfotransferases to Enzymatically Synthesize Keratan Sulfate Oligosaccharides

[Image: see text] Keratan sulfate (KS) is a glycosaminoglycan that is widely expressed in the extracellular matrix of various tissue types, where it is involved in many biological processes. Herein, we describe a chemo-enzymatic approach to preparing well-defined KS oligosaccharides by exploiting th...

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Detalles Bibliográficos
Autores principales: Wu, Yunfei, Vos, Gaël M., Huang, Chin, Chapla, Digantkumar, Kimpel, Anne L. M., Moremen, Kelley W., de Vries, Robert P., Boons, Geert-Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685434/
https://www.ncbi.nlm.nih.gov/pubmed/38034954
http://dx.doi.org/10.1021/jacsau.3c00488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685434/
https://www.ncbi.nlm.nih.gov/pubmed/38034954
http://dx.doi.org/10.1021/jacsau.3c00488

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