Cargando…

Exploiting Substrate Specificities of 6-O-Sulfotransferases to Enzymatically Synthesize Keratan Sulfate Oligosaccharides

[Image: see text] Keratan sulfate (KS) is a glycosaminoglycan that is widely expressed in the extracellular matrix of various tissue types, where it is involved in many biological processes. Herein, we describe a chemo-enzymatic approach to preparing well-defined KS oligosaccharides by exploiting th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Yunfei, Vos, Gaël M., Huang, Chin, Chapla, Digantkumar, Kimpel, Anne L. M., Moremen, Kelley W., de Vries, Robert P., Boons, Geert-Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685434/ https://www.ncbi.nlm.nih.gov/pubmed/38034954 http://dx.doi.org/10.1021/jacsau.3c00488

Ejemplares similares

An automated platform for the enzyme-mediated assembly of complex oligosaccharides
por: Li, Tiehai, et al.
Publicado: (2019)

Downstream Products are Potent Inhibitors of the Heparan Sulfate 2-O-Sulfotransferase
por: Thieker, David F., et al.
Publicado: (2018)

Author Correction: Downstream Products are Potent Inhibitors of the Heparan Sulfate 2-O-Sulfotransferase
por: Thieker, David F., et al.
Publicado: (2020)

Sequential in vitro enzymatic N-glycoprotein modification reveals site-specific rates of glycoenzyme processing
por: Adams, Trevor M., et al.
Publicado: (2022)

Contributions of Chondroitin Sulfate, Keratan Sulfate and N-linked Oligosaccharides to Inhibition of Neurite Outgrowth by Aggrecan
por: Hering, Thomas M., et al.
Publicado: (2020)

Tissue-specific expression of carbohydrate sulfotransferases drives keratan sulfate biosynthesis in the notochord and otic vesicles of Xenopus embryos
por: Yasuoka, Yuuri
Publicado: (2023)

GlcNAc6ST3 is a keratan sulfate sulfotransferase for the protein-tyrosine phosphatase PTPRZ in the adult brain
por: Narentuya, et al.
Publicado: (2019)

Streamlining the Chemoenzymatic Synthesis of Complex N-Glycans by a Stop and Go Strategy
por: Liu, Lin, et al.
Publicado: (2018)

Chemoenzymatic Synthesis of Heparan Sulfate Oligosaccharides having a Domain Structure
por: Sun, Lifeng, et al.
Publicado: (2022)

Bioinformatic Characterization of Sulfotransferase Provides New Insights for the Exploitation of Sulfated Polysaccharides in Caulerpa
por: Landi, Simone, et al.
Publicado: (2020)

Ablation of Keratan Sulfate Accelerates Early Phase Pathogenesis of ALS
por: Hirano, Kenichi, et al.
Publicado: (2013)

Keratan sulfate, a complex glycosaminoglycan with unique functional capability
por: Caterson, Bruce, et al.
Publicado: (2018)

Role of keratan sulfate expression in human pancreatic cancer malignancy
por: Leiphrakpam, Premila D., et al.
Publicado: (2019)

Glycan remodeled erythrocytes facilitate antigenic characterization of recent A/H3N2 influenza viruses
por: Broszeit, Frederik, et al.
Publicado: (2021)

Sialylated keratan sulfate proteoglycans are Siglec-8 ligands in human airways
por: Gonzalez-Gil, Anabel, et al.
Publicado: (2018)

Preparation of Tyrosylprotein Sulfotransferases for In Vitro One-Pot Enzymatic Synthesis of Sulfated Proteins/Peptides
por: Wang, Chen-Chu, et al.
Publicado: (2018)

Two subpopulations of differentiated chondrocytes identified with a monoclonal antibody to keratan sulfate
Publicado: (1985)

Keratan sulfate expression in microglia is diminished in the spinal cord in experimental autoimmune neuritis
por: Matsui, H, et al.
Publicado: (2013)

Identification of keratan sulfate disaccharide at C-3 position of glucuronate of chondroitin sulfate from Mactra chinensis
por: Higashi, Kyohei, et al.
Publicado: (2016)

Enzymatic Production of Chondroitin Oligosaccharides and Its Sulfate Derivatives
por: Zhang, Weijiao, et al.
Publicado: (2022)

Nematodes join the family of chondroitin sulfate-synthesizing organisms: Identification of an active chondroitin sulfotransferase in Caenorhabditis elegans
por: Dierker, Tabea, et al.
Publicado: (2016)

Variable posttranslational modifications of severe acute respiratory syndrome coronavirus 2 nucleocapsid protein
por: Supekar, Nitin T, et al.
Publicado: (2021)

Elucidating Human Milk Oligosaccharide biosynthetic genes through network-based multi-omics integration
por: Kellman, Benjamin P., et al.
Publicado: (2022)

Keratan Sulfate Phenotype in the β-1,3-N-Acetylglucosaminyltransferase-7–Null Mouse Cornea
por: Littlechild, Stacy L., et al.
Publicado: (2018)

Urinary proteomics links keratan sulfate degradation and lysosomal enzymes to early type 1 diabetes
por: Van, Julie A. D., et al.
Publicado: (2020)

Involvement of langerin in the protective function of a keratan sulfate-based disaccharide in an emphysema mouse model
por: Ohkawa, Yuki, et al.
Publicado: (2023)

Combinatorial virtual library screening analysis of antithrombin binding oligosaccharide motif generation by heparan sulfate 3-O-Sulfotransferase 1()
por: Sankaranarayanan, Nehru Viji, et al.
Publicado: (2020)

Structural Characterization and Interaction with RCA(120) of a Highly Sulfated Keratan Sulfate from Blue Shark (Prionace glauca) Cartilage
por: Li, Qinying, et al.
Publicado: (2018)

Comparison of Liquid Chromatography–Tandem Mass Spectrometry and Sandwich ELISA for Determination of Keratan Sulfate in Plasma and Urine
por: Hintze, Jonathan P., et al.
Publicado: (2011)

Dietary Keratan Sulfate from Shark Cartilage Modulates Gut Microbiota and Increases the Abundance of Lactobacillus spp.
por: Shang, Qingsen, et al.
Publicado: (2016)

Structural insight into the binding of human galectins to corneal keratan sulfate, its desulfated form and related saccharides
por: Miller, Michelle C., et al.
Publicado: (2020)

Beta3Gn-T7 Is a Keratan Sulfate β1,3 N-Acetylglucosaminyltransferase in the Adult Brain
por: Takeda-Uchimura, Yoshiko, et al.
Publicado: (2022)

The Emerging Roles of Heparan Sulfate 3-O-Sulfotransferases in Cancer
por: Denys, Agnès, et al.
Publicado: (2019)

Improvement of the stability and catalytic efficiency of heparan sulfate N-sulfotransferase for preparing N-sulfated heparosan
por: Xi, Xintong, et al.
Publicado: (2023)

Regulation of Notch signaling by Drosophila heparan sulfate 3-O sulfotransferase
por: Kamimura, Keisuke, et al.
Publicado: (2004)

Overexpression of heparan sulfate 6-O-sulfotransferase-2 in colorectal cancer
por: HATABE, SHIGERU, et al.
Publicado: (2013)

Bone Matrix Proteins: Isolation and Characterization of a Novel Cell-binding Keratan Sulfate Proteoglycan (Osteoadherin) from Bovine Bone
por: Wendel, Mikael, et al.
Publicado: (1998)

Keratan sulfate-based glycomimetics using Langerin as a target for COPD: lessons from studies on Fut8 and core fucose
por: Ohkawa, Yuki, et al.
Publicado: (2021)

Deciphering the substrate recognition mechanisms of the heparan sulfate 3-O-sulfotransferase-3
por: Wander, Rylee, et al.
Publicado: (2021)

Serum keratan sulfate transiently increases in the early stage of osteoarthritis during strenuous running of rats: protective effect of intraarticular hyaluronan injection
por: Tang, Tao, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_399flcmc7r0683denvcelfo0eb