Cargando…

Breast cancer surveillance in BRCA positive Sri Lankan women: health equity for a high-risk group at a limited resource setting

BACKGROUND: BRCA1 and BRCA2 pathogenic variants account for 90% of hereditary breast malignancies, incurring a lifetime breast cancer risk of 85% and 40–45% respectively, in affected individuals. Well-resourced health care settings offer genetic counselling and genetic screening for susceptible indi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liyanage, Udari Apsara, Sirisena, Nirmala Dushyanthi, Deshapriya, Pushpika Chathuranga, Dissanayake, Vajira Harshadeva Weerabaddana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685476/ https://www.ncbi.nlm.nih.gov/pubmed/38017478 http://dx.doi.org/10.1186/s12905-023-02797-z

Ejemplares similares

Genetic Variants Associated with Clinicopathological Profiles in Sporadic Breast Cancer in Sri Lankan Women
por: Sirisena, Nirmala Dushyanthi, et al.
Publicado: (2018)

Novel mutation in the SLC12A3 gene in a Sri Lankan family with Gitelman syndrome & coexistent diabetes: a case report
por: Subasinghe, Chandrika Jayakanthi, et al.
Publicado: (2017)

The pattern of KRAS mutations in metastatic colorectal cancer: a retrospective audit from Sri Lanka
por: Sirisena, Nirmala Dushyanthi, et al.
Publicado: (2017)

Genetic determinants of sporadic breast cancer in Sri Lankan women
por: Sirisena, Nirmala Dushyanthi, et al.
Publicado: (2018)

Genotype data for single nucleotide polymorphism markers in sporadic breast cancer related genes in a Sri Lankan case–control cohort of postmenopausal women
por: Sirisena, Nirmala Dushyanthi, et al.
Publicado: (2019)

Split hand/foot malformation with long bone deficiency associated with BHLHA9 gene duplication: a case report and review of literature
por: Paththinige, Chamara Sampath, et al.
Publicado: (2019)

Design and implementation of a novel pharmacogenetic assay for the identification of the CYP2D6*10 genetic variant
por: Ranadeva, Nadeeka Dimuthu Kumari, et al.
Publicado: (2022)

The Frequency and Spectrum of Chromosomal Translocations in a Cohort of Sri Lankans
por: Paththinige, Chamara S., et al.
Publicado: (2019)

The first Sri Lankan family with Dent disease-1 due to a pathogenic variant in the CLCN5 gene: a case report
por: Ranawaka, Randula, et al.
Publicado: (2017)

A Case Series of Five Sri Lankan Patients with Ovotesticular Disorder of Sex Development
por: Wettasinghe, Kalum T., et al.
Publicado: (2012)

Germline variants of uncertain significance, their frequency, and clinico-pathological features in a cohort of Sri Lankan patients with hereditary breast cancer
por: Gunawardena, Kawmadi, et al.
Publicado: (2023)

Functional evaluation of five BRCA2 unclassified variants identified in a Sri Lankan cohort with inherited cancer syndromes using a mouse embryonic stem cell-based assay
por: Sirisena, Nirmala, et al.
Publicado: (2020)

Genetics and genomic medicine in Sri Lanka
por: Sirisena, Nirmala D., et al.
Publicado: (2019)

Relative normalized luciferase activity for the recombinant vector constructs carrying the ancestral and variant alleles for XRCC2:rs3218550 and PHB:rs6917
por: Sirisena, Nirmala Dushyanthi, et al.
Publicado: (2018)

A Sri Lankan child with 49,XXXXY syndrome
por: Dissanayake, Vajira H. W., et al.
Publicado: (2010)

Implementation of genomic medicine in Sri Lanka: Initial experience and challenges
por: Sirisena, Nirmala D., et al.
Publicado: (2016)

Migration of Sri Lankan medical specialists
por: De Silva, A Pubudu, et al.
Publicado: (2013)

The burden of hospital admissions for skeletal dysplasias in Sri Lanka: a population-based study
por: Kolambage, Yasas D., et al.
Publicado: (2023)

Genetic variants in the cytochrome P450 2D6 gene in the Sri Lankan population
por: Tharanga, T. D. Praveen, et al.
Publicado: (2013)

Frequency of Hereditary Hemochromatosis Gene (HFE) Variants in Sri Lankan Transfusion-Dependent Beta-Thalassemia Patients and Their Association With the Serum Ferritin Level
por: Padeniya, Padmapani, et al.
Publicado: (2022)

Single Nucleotide Variants of Candidate Genes in Aggrecan Metabolic Pathway Are Associated with Lumbar Disc Degeneration and Modic Changes
por: Perera, Romain Shanil, et al.
Publicado: (2017)

Associations between disc space narrowing, anterior osteophytes and disability in chronic mechanical low back pain: a cross sectional study
por: Perera, Romain Shanil, et al.
Publicado: (2017)

Variants of ACAN are associated with severity of lumbar disc herniation in patients with chronic low back pain
por: Perera, Romain Shanil, et al.
Publicado: (2017)

Copy Number Variants Captured by the Array Comparative Genomic Hybridization in a Cohort of Patients Affected with Hereditary Colorectal Cancer in Sri Lanka: The First CNV Analysis Study of the Hereditary Colorectal Cancer in the Sri Lankan Population
por: Wijesiriwardhana, Prabhavi, et al.
Publicado: (2021)

Family Planning Prevalence Among Postpartum Mothers Attending Child Welfare Clinics – A Sri Lankan Experience
por: Agampodi, Suneth B, et al.
Publicado: (2009)

Strategies for Genomic Medicine Education in Low- and Middle-Income Countries
por: Sirisena, Nirmala D., et al.
Publicado: (2019)

Profile of Hashimoto's Thyroiditis in Sri Lankans: Is There an Increased Risk of Ancillary Pathologies in Hashimoto's Thyroiditis?
por: Siriweera, Eranga Himalee, et al.
Publicado: (2010)

Vitamin D Deficiency in Dengue Hemorrhagic Fever and Dengue Shock Syndrome among Sri Lankan Children: A Case-Control Study
por: Dissanayake, Sharmila, et al.
Publicado: (2021)

Electrophoretic mobility shift assays implicate XRCC2:rs3218550C>T as a potential low-penetrant susceptibility allele for sporadic breast cancer
por: Sirisena, Nirmala D., et al.
Publicado: (2019)

A novel mutation in SLC37A4 gene in a Sri Lankan boy with glycogen storage disease type Ib associated with very early onset neutropenia
por: Dissanayake, Vajira HW, et al.
Publicado: (2011)

Genetic diversity of variants involved in drug response and metabolism in Sri Lankan populations: implications for clinical implementation of pharmacogenomics
por: Chan, Sze Ling, et al.
Publicado: (2016)

Thinness negatively affects lung function among Sri Lankan children
por: Senevirathna, Niroshani, et al.
Publicado: (2022)

Parathyroid hormone in Sri Lankan pregnant women: Vitamin D and other determinants
por: Kaneshapillai, Anusha, et al.
Publicado: (2021)

Concomitant Guillain–Barré Syndrome in a young Sri Lankan male with severe ulcerative colitis
por: Jayasundara, Jayasundara Mudiyanselage Hishali Dahami, et al.
Publicado: (2022)

Acceptability of home fortification with multiple micro-nutrients among Sri Lankan children
por: Liyanage, G., et al.
Publicado: (2021)

Elevated levels of whole blood nickel in a group of Sri Lankan women with endometriosis: a case control study
por: Silva, Nalinda, et al.
Publicado: (2013)

Vitamin D knowledge and sun exposure practices among Sri Lankan healthcare undergraduates
por: Liyanage, Guwani, et al.
Publicado: (2022)

Vitamin D level and bone profile among 1- to 5-year-old children in Galle municipality and Bope-Poddala areas in Sri Lanka
por: Jayawardana, Pushpika, et al.
Publicado: (2023)

Analysis of BRCA1and BRCA2 large genomic rearrangements in Sri Lankan familial breast cancer patients and at risk individuals
por: De Silva, Sumadee, et al.
Publicado: (2014)

Spread of resistant gram negatives in a Sri Lankan intensive care unit
por: Tissera, Kavinda, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_mfg7q5102sagcn2m50vtc1dsgl