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IGF2 deficiency promotes liver aging through mitochondrial dysfunction and upregulated CEBPB signaling in d-galactose-induced aging mice

BACKGROUND: Liver aging, marked by cellular senescence and low-grade inflammation, heightens susceptibility to chronic liver disease and worsens its prognosis. Insulin-like growth factor 2 (IGF2) has been implicated in numerous aging-related diseases. Nevertheless, its role and underlying molecular...

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Detalles Bibliográficos
Autores principales:	Zhou, Xiaohai, Tan, Bowen, Gui, Weiwei, Zhou, Caiping, Zhao, Hanxin, Lin, Xihua, Li, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685569/ https://www.ncbi.nlm.nih.gov/pubmed/38017373 http://dx.doi.org/10.1186/s10020-023-00752-0

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