Towards a partial order graph for interactive pharmacophore exploration: extraction of pharmacophores activity delta

This paper presents a novel approach called Pharmacophore Activity Delta for extracting outstanding pharmacophores from a chemogenomic dataset, with a specific focus on a kinase target known as BCR-ABL. The method involves constructing a Hasse diagram, referred to as the pharmacophore network, by ut...

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Detalles Bibliográficos
Autores principales: Lehembre, Etienne, Giovannini, Johanna, Geslin, Damien, Lepailleur, Alban, Lamotte, Jean-Luc, Auber, David, Ouali, Abdelkader, Cremilleux, Bruno, Zimmermann, Albrecht, Cuissart, Bertrand, Bureau, Ronan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685576/
https://www.ncbi.nlm.nih.gov/pubmed/38031134
http://dx.doi.org/10.1186/s13321-023-00782-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685576/
https://www.ncbi.nlm.nih.gov/pubmed/38031134
http://dx.doi.org/10.1186/s13321-023-00782-0

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