In silico prediction of bioequivalence of atorvastatin tablets based on GastroPlus™ software

The prediction of intestinal absorption of various drugs based on computer simulations has been a reality. However, in vivo pharmacokinetic simulations and virtual bioequivalence evaluation based on GastroPlus™ have not been found. This study aimed to simulate plasma concentrations with different di...

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Detalles Bibliográficos
Autores principales: Wang, Lu, Chen, Jinliang, Chen, Wenjun, Ruan, Zourong, Lou, Honggang, Yang, Dandan, Jiang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685666/
https://www.ncbi.nlm.nih.gov/pubmed/38017512
http://dx.doi.org/10.1186/s40360-023-00689-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685666/
https://www.ncbi.nlm.nih.gov/pubmed/38017512
http://dx.doi.org/10.1186/s40360-023-00689-4

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