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In silico prediction of bioequivalence of atorvastatin tablets based on GastroPlus™ software
The prediction of intestinal absorption of various drugs based on computer simulations has been a reality. However, in vivo pharmacokinetic simulations and virtual bioequivalence evaluation based on GastroPlus™ have not been found. This study aimed to simulate plasma concentrations with different di...
Autores principales: | Wang, Lu, Chen, Jinliang, Chen, Wenjun, Ruan, Zourong, Lou, Honggang, Yang, Dandan, Jiang, Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685666/ https://www.ncbi.nlm.nih.gov/pubmed/38017512 http://dx.doi.org/10.1186/s40360-023-00689-4 |
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