ADAR1 suppression causes interferon signaling and transposable element transcript accumulation in human astrocytes

Neuroinflammation is a central mechanism of brain aging and Alzheimer’s disease (AD), but the exact causes of age- and AD-related neuroinflammation are incompletely understood. One potential modulator of neuroinflammation is the enzyme adenosine deaminase acting on RNA 1 (ADAR1), which regulates the...

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Detalles Bibliográficos
Autores principales: McEntee, Cali M., Cavalier, Alyssa N., LaRocca, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685929/
https://www.ncbi.nlm.nih.gov/pubmed/38035265
http://dx.doi.org/10.3389/fnmol.2023.1263369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685929/
https://www.ncbi.nlm.nih.gov/pubmed/38035265
http://dx.doi.org/10.3389/fnmol.2023.1263369

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