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Assessment and predictive ability of the absolute neutrophil count in peripheral blood for in vivo CAR T cells expansion and CRS

BACKGROUND: Chimeric antigen receptor (CAR) T cell therapy is an advanced and effective immunotherapy for relapsed or refractory B-cell malignancies. High expansion of CAR T cells in vivo and durable antitumor activity indicate a persistent therapeutic response. However, this treatment is linked to...

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Detalles Bibliográficos
Autores principales:	Zhang, Man, Long, Xiaolu, Xiao, Yi, Jin, Jin, Chen, Caixia, Meng, Jiao, Liu, Wanying, Liu, Aichun, Chen, Liting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Immunotherapy Biomarkers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685953/ https://www.ncbi.nlm.nih.gov/pubmed/38016717 http://dx.doi.org/10.1136/jitc-2023-007790

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