Rapid discovery of terpene tailoring enzymes for total biosynthesis

Twenty oxygenated aristolochene congeners were rapidly synthesised by combining genes from four different fungal pathways in the fungal host organism Aspergillus oryzae. Compounds produced in a single step include the natural product hypoxylan A and an epimer of guignaderemophilane C. A new fungal a...

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Detalles Bibliográficos
Autores principales: Sun, Yunlong, Gerke, Jennifer, Becker, Kevin, Kuhnert, Eric, Verwaaijen, Bart, Wibberg, Daniel, Kalinowski, Jörn, Stadler, Marc, Cox, Russell J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686045/
https://www.ncbi.nlm.nih.gov/pubmed/38033887
http://dx.doi.org/10.1039/d3sc04172g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686045/
https://www.ncbi.nlm.nih.gov/pubmed/38033887
http://dx.doi.org/10.1039/d3sc04172g

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