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Rapid discovery of terpene tailoring enzymes for total biosynthesis
Twenty oxygenated aristolochene congeners were rapidly synthesised by combining genes from four different fungal pathways in the fungal host organism Aspergillus oryzae. Compounds produced in a single step include the natural product hypoxylan A and an epimer of guignaderemophilane C. A new fungal a...
Autores principales: | Sun, Yunlong, Gerke, Jennifer, Becker, Kevin, Kuhnert, Eric, Verwaaijen, Bart, Wibberg, Daniel, Kalinowski, Jörn, Stadler, Marc, Cox, Russell J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686045/ https://www.ncbi.nlm.nih.gov/pubmed/38033887 http://dx.doi.org/10.1039/d3sc04172g |
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