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GDF8 inhibition enhances musculoskeletal recovery and mitigates posttraumatic osteoarthritis following joint injury

Musculoskeletal disorders contribute substantially to worldwide disability. Anterior cruciate ligament (ACL) tears result in unresolved muscle weakness and posttraumatic osteoarthritis (PTOA). Growth differentiation factor 8 (GDF8) has been implicated in the pathogenesis of musculoskeletal degenerat...

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Detalles Bibliográficos
Autores principales:	Brightwell, Camille R., Latham, Christine M., Keeble, Alexander R., Thomas, Nicholas T., Owen, Allison M., Reeves, Kelsey A., Long, Douglas E., Patrick, Matthew, Gonzalez-Velez, Sara, Abed, Varag, Annamalai, Ramkumar T., Jacobs, Cale, Conley, Caitlin E., Hawk, Gregory S., Stone, Austin V., Fry, Jean L., Thompson, Katherine L., Johnson, Darren L., Noehren, Brian, Fry, Christopher S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686569/ https://www.ncbi.nlm.nih.gov/pubmed/38019905 http://dx.doi.org/10.1126/sciadv.adi9134

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