Cargando…

Granulocyte Colony-stimulating Factor-associated Aortitis on Gallium Scintigraphy

Aortitis is a rare adverse event associated with granulocyte colony-stimulating factor (G-CSF). Contrast-enhanced computed tomography (CECT) is widely used to diagnose G-CSF-associated aortitis. However, the usefulness of gallium scintigraphy for the diagnosis of G-CSF-associated aortitis is unknown...

Descripción completa

Detalles Bibliográficos
Autores principales: Ozaki, Haruka, Takemura, Kohji, Kizawa, Rika, Yamaguchi, Takeshi, Komiyama, Chinatsu, Tachi, Masato, Maruno, Hirotaka, Tanabe, Yuko, Suyama, Koichi, Miura, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686721/
https://www.ncbi.nlm.nih.gov/pubmed/36948620
http://dx.doi.org/10.2169/internalmedicine.1453-22
Descripción
Sumario:Aortitis is a rare adverse event associated with granulocyte colony-stimulating factor (G-CSF). Contrast-enhanced computed tomography (CECT) is widely used to diagnose G-CSF-associated aortitis. However, the usefulness of gallium scintigraphy for the diagnosis of G-CSF-associated aortitis is unknown. We herein report a set of pre- and post-treatment gallium scintigrams of a patient with G-CSF-associated aortitis. During the diagnosis, gallium scintigraphy revealed hot spots on the arterial walls that appeared inflamed on CECT. Both the CECT and gallium scintigraphy findings disappeared. Gallium scintigraphy can be a supportive diagnostic tool for G-CSF-associated aortitis, especially in patients with an impaired renal function or allergy to iodine contrast.