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Granulocyte Colony-stimulating Factor-associated Aortitis on Gallium Scintigraphy
Aortitis is a rare adverse event associated with granulocyte colony-stimulating factor (G-CSF). Contrast-enhanced computed tomography (CECT) is widely used to diagnose G-CSF-associated aortitis. However, the usefulness of gallium scintigraphy for the diagnosis of G-CSF-associated aortitis is unknown...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Internal Medicine
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686721/ https://www.ncbi.nlm.nih.gov/pubmed/36948620 http://dx.doi.org/10.2169/internalmedicine.1453-22 |
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author | Ozaki, Haruka Takemura, Kohji Kizawa, Rika Yamaguchi, Takeshi Komiyama, Chinatsu Tachi, Masato Maruno, Hirotaka Tanabe, Yuko Suyama, Koichi Miura, Yuji |
author_facet | Ozaki, Haruka Takemura, Kohji Kizawa, Rika Yamaguchi, Takeshi Komiyama, Chinatsu Tachi, Masato Maruno, Hirotaka Tanabe, Yuko Suyama, Koichi Miura, Yuji |
author_sort | Ozaki, Haruka |
collection | PubMed |
description | Aortitis is a rare adverse event associated with granulocyte colony-stimulating factor (G-CSF). Contrast-enhanced computed tomography (CECT) is widely used to diagnose G-CSF-associated aortitis. However, the usefulness of gallium scintigraphy for the diagnosis of G-CSF-associated aortitis is unknown. We herein report a set of pre- and post-treatment gallium scintigrams of a patient with G-CSF-associated aortitis. During the diagnosis, gallium scintigraphy revealed hot spots on the arterial walls that appeared inflamed on CECT. Both the CECT and gallium scintigraphy findings disappeared. Gallium scintigraphy can be a supportive diagnostic tool for G-CSF-associated aortitis, especially in patients with an impaired renal function or allergy to iodine contrast. |
format | Online Article Text |
id | pubmed-10686721 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | The Japanese Society of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-106867212023-11-30 Granulocyte Colony-stimulating Factor-associated Aortitis on Gallium Scintigraphy Ozaki, Haruka Takemura, Kohji Kizawa, Rika Yamaguchi, Takeshi Komiyama, Chinatsu Tachi, Masato Maruno, Hirotaka Tanabe, Yuko Suyama, Koichi Miura, Yuji Intern Med Case Report Aortitis is a rare adverse event associated with granulocyte colony-stimulating factor (G-CSF). Contrast-enhanced computed tomography (CECT) is widely used to diagnose G-CSF-associated aortitis. However, the usefulness of gallium scintigraphy for the diagnosis of G-CSF-associated aortitis is unknown. We herein report a set of pre- and post-treatment gallium scintigrams of a patient with G-CSF-associated aortitis. During the diagnosis, gallium scintigraphy revealed hot spots on the arterial walls that appeared inflamed on CECT. Both the CECT and gallium scintigraphy findings disappeared. Gallium scintigraphy can be a supportive diagnostic tool for G-CSF-associated aortitis, especially in patients with an impaired renal function or allergy to iodine contrast. The Japanese Society of Internal Medicine 2023-03-22 2023-11-01 /pmc/articles/PMC10686721/ /pubmed/36948620 http://dx.doi.org/10.2169/internalmedicine.1453-22 Text en Copyright © 2023 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Ozaki, Haruka Takemura, Kohji Kizawa, Rika Yamaguchi, Takeshi Komiyama, Chinatsu Tachi, Masato Maruno, Hirotaka Tanabe, Yuko Suyama, Koichi Miura, Yuji Granulocyte Colony-stimulating Factor-associated Aortitis on Gallium Scintigraphy |
title | Granulocyte Colony-stimulating Factor-associated Aortitis on Gallium Scintigraphy |
title_full | Granulocyte Colony-stimulating Factor-associated Aortitis on Gallium Scintigraphy |
title_fullStr | Granulocyte Colony-stimulating Factor-associated Aortitis on Gallium Scintigraphy |
title_full_unstemmed | Granulocyte Colony-stimulating Factor-associated Aortitis on Gallium Scintigraphy |
title_short | Granulocyte Colony-stimulating Factor-associated Aortitis on Gallium Scintigraphy |
title_sort | granulocyte colony-stimulating factor-associated aortitis on gallium scintigraphy |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686721/ https://www.ncbi.nlm.nih.gov/pubmed/36948620 http://dx.doi.org/10.2169/internalmedicine.1453-22 |
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