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Granulocyte Colony-stimulating Factor-associated Aortitis on Gallium Scintigraphy

Aortitis is a rare adverse event associated with granulocyte colony-stimulating factor (G-CSF). Contrast-enhanced computed tomography (CECT) is widely used to diagnose G-CSF-associated aortitis. However, the usefulness of gallium scintigraphy for the diagnosis of G-CSF-associated aortitis is unknown...

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Autores principales: Ozaki, Haruka, Takemura, Kohji, Kizawa, Rika, Yamaguchi, Takeshi, Komiyama, Chinatsu, Tachi, Masato, Maruno, Hirotaka, Tanabe, Yuko, Suyama, Koichi, Miura, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686721/
https://www.ncbi.nlm.nih.gov/pubmed/36948620
http://dx.doi.org/10.2169/internalmedicine.1453-22
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author Ozaki, Haruka
Takemura, Kohji
Kizawa, Rika
Yamaguchi, Takeshi
Komiyama, Chinatsu
Tachi, Masato
Maruno, Hirotaka
Tanabe, Yuko
Suyama, Koichi
Miura, Yuji
author_facet Ozaki, Haruka
Takemura, Kohji
Kizawa, Rika
Yamaguchi, Takeshi
Komiyama, Chinatsu
Tachi, Masato
Maruno, Hirotaka
Tanabe, Yuko
Suyama, Koichi
Miura, Yuji
author_sort Ozaki, Haruka
collection PubMed
description Aortitis is a rare adverse event associated with granulocyte colony-stimulating factor (G-CSF). Contrast-enhanced computed tomography (CECT) is widely used to diagnose G-CSF-associated aortitis. However, the usefulness of gallium scintigraphy for the diagnosis of G-CSF-associated aortitis is unknown. We herein report a set of pre- and post-treatment gallium scintigrams of a patient with G-CSF-associated aortitis. During the diagnosis, gallium scintigraphy revealed hot spots on the arterial walls that appeared inflamed on CECT. Both the CECT and gallium scintigraphy findings disappeared. Gallium scintigraphy can be a supportive diagnostic tool for G-CSF-associated aortitis, especially in patients with an impaired renal function or allergy to iodine contrast.
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spelling pubmed-106867212023-11-30 Granulocyte Colony-stimulating Factor-associated Aortitis on Gallium Scintigraphy Ozaki, Haruka Takemura, Kohji Kizawa, Rika Yamaguchi, Takeshi Komiyama, Chinatsu Tachi, Masato Maruno, Hirotaka Tanabe, Yuko Suyama, Koichi Miura, Yuji Intern Med Case Report Aortitis is a rare adverse event associated with granulocyte colony-stimulating factor (G-CSF). Contrast-enhanced computed tomography (CECT) is widely used to diagnose G-CSF-associated aortitis. However, the usefulness of gallium scintigraphy for the diagnosis of G-CSF-associated aortitis is unknown. We herein report a set of pre- and post-treatment gallium scintigrams of a patient with G-CSF-associated aortitis. During the diagnosis, gallium scintigraphy revealed hot spots on the arterial walls that appeared inflamed on CECT. Both the CECT and gallium scintigraphy findings disappeared. Gallium scintigraphy can be a supportive diagnostic tool for G-CSF-associated aortitis, especially in patients with an impaired renal function or allergy to iodine contrast. The Japanese Society of Internal Medicine 2023-03-22 2023-11-01 /pmc/articles/PMC10686721/ /pubmed/36948620 http://dx.doi.org/10.2169/internalmedicine.1453-22 Text en Copyright © 2023 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Ozaki, Haruka
Takemura, Kohji
Kizawa, Rika
Yamaguchi, Takeshi
Komiyama, Chinatsu
Tachi, Masato
Maruno, Hirotaka
Tanabe, Yuko
Suyama, Koichi
Miura, Yuji
Granulocyte Colony-stimulating Factor-associated Aortitis on Gallium Scintigraphy
title Granulocyte Colony-stimulating Factor-associated Aortitis on Gallium Scintigraphy
title_full Granulocyte Colony-stimulating Factor-associated Aortitis on Gallium Scintigraphy
title_fullStr Granulocyte Colony-stimulating Factor-associated Aortitis on Gallium Scintigraphy
title_full_unstemmed Granulocyte Colony-stimulating Factor-associated Aortitis on Gallium Scintigraphy
title_short Granulocyte Colony-stimulating Factor-associated Aortitis on Gallium Scintigraphy
title_sort granulocyte colony-stimulating factor-associated aortitis on gallium scintigraphy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686721/
https://www.ncbi.nlm.nih.gov/pubmed/36948620
http://dx.doi.org/10.2169/internalmedicine.1453-22
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