Successful Treatment with Crizotinib to Overcome Drug Resistance Possibly Due to Mesenchymal-epithelial Transition Amplification in a Lung Cancer Patient with the Echinoderm Microtubule-associated Protein-like 4-anaplastic Lymphoma Kinase Fusion Gene

Amplification of the mesenchymal-epithelial transition (MET) gene plays an important role in anticancer drug resistance to anaplastic lymphoma kinase-tyrosine kinase inhibitors (ALK-TKIs) in echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK)-rearranged lung cancer...

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Detalles Bibliográficos
Autores principales: Shiraishi, Tomoko, Yamasaki, Kei, Kidogawa, Moe, Shingu, Tatsuya, Ujimiya, Fuki, Jotatsu, Takanobu, Matsumoto, Shingo, Izumi, Hiroki, Nishida, Chinatsu, Goto, Koichi, Yatera, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686730/
https://www.ncbi.nlm.nih.gov/pubmed/36927974
http://dx.doi.org/10.2169/internalmedicine.1164-22

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