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Comprehensive Analysis of Hemophilia A (CAHEA): Towards Full Characterization of the F8 Gene Variants by Long-Read Sequencing

Background Hemophilia A (HA) is the most frequently occurring X-linked bleeding disorder caused by heterogeneous variants in the F8 gene, one of the largest genes known. Conventional molecular analysis of F8 requires a combination of assays, usually including long-range polymerase chain reaction (L...

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Detalles Bibliográficos
Autores principales:	Liu, Yingdi, Li, Dongzhi, Yu, Dongyi, Liang, Qiaowei, Chen, Guilan, Li, Fucheng, Gao, Lu, Li, Zhuo, Xie, Tiantian, Wu, Le, Mao, Aiping, Wu, Lingqian, Liang, Desheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Georg Thieme Verlag KG 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686748/ https://www.ncbi.nlm.nih.gov/pubmed/37285902 http://dx.doi.org/10.1055/a-2107-0702

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