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SARS-CoV-2 activates the TLR4/MyD88 pathway in human macrophages: A possible correlation with strong pro-inflammatory responses in severe COVID-19

BACKGROUND: Toll-like receptors (TLRs) play a pivotal role in the immunologic response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Exaggerated inflammatory response of innate immune cells, however, may drive morbidity and death in Coronavirus disease 19 (COVID-19). OBJ...

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Detalles Bibliográficos
Autores principales:	Sahanic, Sabina, Hilbe, Richard, Dünser, Christina, Tymoszuk, Piotr, Löffler-Ragg, Judith, Rieder, Dietmar, Trajanoski, Zlatko, Krogsdam, Anne, Demetz, Egon, Yurchenko, Maria, Fischer, Christine, Schirmer, Michael, Theurl, Markus, Lener, Daniela, Hirsch, Jakob, Holfeld, Johannes, Gollmann-Tepeköylü, Can, Zinner, Carl P., Tzankov, Alexandar, Zhang, Shen-Ying, Casanova, Jean-Laurent, Posch, Wilfried, Wilflingseder, Doris, Weiss, Guenter, Tancevski, Ivan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686889/ https://www.ncbi.nlm.nih.gov/pubmed/38034686 http://dx.doi.org/10.1016/j.heliyon.2023.e21893

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