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β-Arrestin2 promotes docetaxel resistance of castration-resistant prostate cancer via promoting hnRNP A1-mediated PKM2 alternative splicing

PURPOSE: To investigate the influence of β-arrestin2 on the docetaxel resistance in castration-resistant prostate cancer (CRPC) and elucidate the underlying molecular mechanisms. METHODS: PC3 and DU145 cells with stable β-arrestin2 overexpression and C4-2 cells with stable β-arrestin2 knockdown, wer...

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Detalles Bibliográficos
Autores principales:	Zhou, Yuhao, Li, Fei, Zou, Bangyu, Zhou, Xiaofeng, Luo, Lianmin, Dong, Sicheng, He, Zhiqing, Zhang, Zhixiong, Liao, Liqiong, Liu, Hongxing, Cai, Chao, Gu, Di, Duan, Xiaolu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686933/ https://www.ncbi.nlm.nih.gov/pubmed/38019357 http://dx.doi.org/10.1007/s12672-023-00740-0

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