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Distinct activation mechanisms of β-arrestin-1 revealed by (19)F NMR spectroscopy
β-Arrestins (βarrs) are functionally versatile proteins that play critical roles in the G-protein-coupled receptor (GPCR) signaling pathways. While it is well established that the phosphorylated receptor tail plays a central role in βarr activation, emerging evidence highlights the contribution from...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686989/ https://www.ncbi.nlm.nih.gov/pubmed/38030602 http://dx.doi.org/10.1038/s41467-023-43694-1 |