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MLX plays a key role in lipid and glucose metabolism in humans: Evidence from in vitro and in vivo studies
BACKGROUND AND AIM: Enhanced hepatic de novo lipogenesis (DNL) has been proposed as an underlying mechanism for the development of NAFLD and insulin resistance. Max-like protein factor X (MLX) acts as a heterodimer binding partner for glucose sensing transcription factors and inhibition of MLX or do...
Autores principales: | Nagarajan, Shilpa R., Livingstone, Eilidh J., Monfeuga, Thomas, Lewis, Lara C., Ali, Shahul Hameed Liyakath, Chandran, Anandhakumar, Dearlove, David J., Neville, Matt J., Chen, Lingyan, Maroteau, Cyrielle, Ruby, Maxwell A., Hodson, Leanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
W.B. Saunders
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687193/ https://www.ncbi.nlm.nih.gov/pubmed/37088121 http://dx.doi.org/10.1016/j.metabol.2023.155563 |
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