High cell-free DNA is associated with disease progression, inflammasome activation and elevated levels of inflammasome-related cytokine IL-18 in patients with myelofibrosis

Myelofibrosis (MF) is a clonal hematopoietic stem cell disorder classified among chronic myeloproliferative neoplasms, characterized by exacerbated myeloid and megakaryocytic proliferation and bone marrow fibrosis. It is induced by driver (JAK2/CALR/MPL) and high molecular risk mutations coupled to...

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Detalles Bibliográficos
Autores principales: De Luca, Geraldine, Lev, Paola R., Camacho, Maria F., Goette, Nora P., Sackmann, Federico, Castro Ríos, Miguel A., Moiraghi, Beatriz, Cortes Guerrieri, Veronica, Bendek, Georgina, Carricondo, Emiliano, Enrico, Alicia, Vallejo, Veronica, Varela, Ana, Khoury, Marina, Gutierrez, Marina, Larripa, Irene B., Marta, Rosana F., Glembotsky, Ana C., Heller, Paula G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687201/
https://www.ncbi.nlm.nih.gov/pubmed/38035089
http://dx.doi.org/10.3389/fimmu.2023.1161832

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