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Effective sequential combined therapy with carboplatin and a CDC7 inhibitor in ovarian cancer
BACKGROUND: The enhancement of DNA damage repair is one of the important mechanisms of platinum resistance. Protein cell division cycle 7 (CDC7) is a conserved serine/threonine kinase that plays important roles in the initiation of DNA replication and is associated with chemotherapy resistance in ov...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687335/ https://www.ncbi.nlm.nih.gov/pubmed/37992591 http://dx.doi.org/10.1016/j.tranon.2023.101825 |