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Effective sequential combined therapy with carboplatin and a CDC7 inhibitor in ovarian cancer

BACKGROUND: The enhancement of DNA damage repair is one of the important mechanisms of platinum resistance. Protein cell division cycle 7 (CDC7) is a conserved serine/threonine kinase that plays important roles in the initiation of DNA replication and is associated with chemotherapy resistance in ov...

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Detalles Bibliográficos
Autores principales: Li, Junping, Hu, Hong, He, Jinping, Hu, Yuling, Liu, Manting, Cao, Bihui, Chen, Dongni, Ye, Xiaodie, Zhang, Jian, Zhang, Zhiru, Long, Wen, Lian, Hui, Chen, Deji, Chen, Likun, Yang, Lili, Zhang, Zhenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687335/
https://www.ncbi.nlm.nih.gov/pubmed/37992591
http://dx.doi.org/10.1016/j.tranon.2023.101825