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Intestinal flora and linear growth in children
The gut microbiota plays a critical role in human growth and development as well as the regulation of human pathophysiological processes. According to research, the gut microbiota controls the host's growth and development in areas such as nutrition, metabolism, endocrine hormones, and immune m...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687454/ https://www.ncbi.nlm.nih.gov/pubmed/38034825 http://dx.doi.org/10.3389/fped.2023.1252035 |
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author | He, Pingsihua Shen, Xingyuan Guo, Sheng |
author_facet | He, Pingsihua Shen, Xingyuan Guo, Sheng |
author_sort | He, Pingsihua |
collection | PubMed |
description | The gut microbiota plays a critical role in human growth and development as well as the regulation of human pathophysiological processes. According to research, the gut microbiota controls the host's growth and development in areas such as nutrition, metabolism, endocrine hormones, and immune modulation. The human gut microbiota has an important role in child and adolescent growth, especially when nutritional conditions are poor. In this review, we focus on recent findings about the gut microbiota's influence on child growth, including the relationship between the gut microbiota and linear growth during pregnancy, infancy, childhood, and adolescence. Furthermore, we also review some mechanisms by which intestinal flora influence the host's linear growth. Although the data supports a link between intestinal flora and linear development in children, our review has limitations that prohibit us from fully verifying the causal relationship between gut flora and linear development in children. Improving the gut microbiota, in conjunction with renutrition techniques, has the potential to ameliorate the growth and development impairments currently associated with chronic illness and malnutrition in children. |
format | Online Article Text |
id | pubmed-10687454 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-106874542023-11-30 Intestinal flora and linear growth in children He, Pingsihua Shen, Xingyuan Guo, Sheng Front Pediatr Pediatrics The gut microbiota plays a critical role in human growth and development as well as the regulation of human pathophysiological processes. According to research, the gut microbiota controls the host's growth and development in areas such as nutrition, metabolism, endocrine hormones, and immune modulation. The human gut microbiota has an important role in child and adolescent growth, especially when nutritional conditions are poor. In this review, we focus on recent findings about the gut microbiota's influence on child growth, including the relationship between the gut microbiota and linear growth during pregnancy, infancy, childhood, and adolescence. Furthermore, we also review some mechanisms by which intestinal flora influence the host's linear growth. Although the data supports a link between intestinal flora and linear development in children, our review has limitations that prohibit us from fully verifying the causal relationship between gut flora and linear development in children. Improving the gut microbiota, in conjunction with renutrition techniques, has the potential to ameliorate the growth and development impairments currently associated with chronic illness and malnutrition in children. Frontiers Media S.A. 2023-11-16 /pmc/articles/PMC10687454/ /pubmed/38034825 http://dx.doi.org/10.3389/fped.2023.1252035 Text en © 2023 He, Shen and Guo. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Pediatrics He, Pingsihua Shen, Xingyuan Guo, Sheng Intestinal flora and linear growth in children |
title | Intestinal flora and linear growth in children |
title_full | Intestinal flora and linear growth in children |
title_fullStr | Intestinal flora and linear growth in children |
title_full_unstemmed | Intestinal flora and linear growth in children |
title_short | Intestinal flora and linear growth in children |
title_sort | intestinal flora and linear growth in children |
topic | Pediatrics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687454/ https://www.ncbi.nlm.nih.gov/pubmed/38034825 http://dx.doi.org/10.3389/fped.2023.1252035 |
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