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An unusual cause of progressive dyspnoea, pulmonary nodules and pleural effusions

Eosinophilic granulomatosis with polyangiitis (EGPA) is part of the ANCA‐associated vasculitides, although ANCA‐negative presentations are not infrequent. Asthma, allergic rhinitis and peripheral eosinophilia are classic associations although pleural effusions are an uncommon manifestation of EGPA....

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Autores principales: Venkatesan, Sudharsan, Ramnani, Bharti, Klebe, Sonja, Mo, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687589/
https://www.ncbi.nlm.nih.gov/pubmed/38045824
http://dx.doi.org/10.1002/rcr2.1261
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author Venkatesan, Sudharsan
Ramnani, Bharti
Klebe, Sonja
Mo, Lin
author_facet Venkatesan, Sudharsan
Ramnani, Bharti
Klebe, Sonja
Mo, Lin
author_sort Venkatesan, Sudharsan
collection PubMed
description Eosinophilic granulomatosis with polyangiitis (EGPA) is part of the ANCA‐associated vasculitides, although ANCA‐negative presentations are not infrequent. Asthma, allergic rhinitis and peripheral eosinophilia are classic associations although pleural effusions are an uncommon manifestation of EGPA. We describe a 35‐year old Caucasian adult with asthma who presented with progressive dyspnoea, cough, peripheral eosinophilia and imaging that showed pulmonary nodules with pleural effusions. Biopsy with histopathological review confirmed the diagnosis of EGPA with steroid therapy resulting in significant resolution of symptoms and imaging findings.
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spelling pubmed-106875892023-12-01 An unusual cause of progressive dyspnoea, pulmonary nodules and pleural effusions Venkatesan, Sudharsan Ramnani, Bharti Klebe, Sonja Mo, Lin Respirol Case Rep Case Reports Eosinophilic granulomatosis with polyangiitis (EGPA) is part of the ANCA‐associated vasculitides, although ANCA‐negative presentations are not infrequent. Asthma, allergic rhinitis and peripheral eosinophilia are classic associations although pleural effusions are an uncommon manifestation of EGPA. We describe a 35‐year old Caucasian adult with asthma who presented with progressive dyspnoea, cough, peripheral eosinophilia and imaging that showed pulmonary nodules with pleural effusions. Biopsy with histopathological review confirmed the diagnosis of EGPA with steroid therapy resulting in significant resolution of symptoms and imaging findings. John Wiley & Sons, Ltd 2023-11-30 /pmc/articles/PMC10687589/ /pubmed/38045824 http://dx.doi.org/10.1002/rcr2.1261 Text en © 2023 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Venkatesan, Sudharsan
Ramnani, Bharti
Klebe, Sonja
Mo, Lin
An unusual cause of progressive dyspnoea, pulmonary nodules and pleural effusions
title An unusual cause of progressive dyspnoea, pulmonary nodules and pleural effusions
title_full An unusual cause of progressive dyspnoea, pulmonary nodules and pleural effusions
title_fullStr An unusual cause of progressive dyspnoea, pulmonary nodules and pleural effusions
title_full_unstemmed An unusual cause of progressive dyspnoea, pulmonary nodules and pleural effusions
title_short An unusual cause of progressive dyspnoea, pulmonary nodules and pleural effusions
title_sort unusual cause of progressive dyspnoea, pulmonary nodules and pleural effusions
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687589/
https://www.ncbi.nlm.nih.gov/pubmed/38045824
http://dx.doi.org/10.1002/rcr2.1261
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