FastCAR: fast correction for ambient RNA to facilitate differential gene expression analysis in single-cell RNA-sequencing datasets

Cell type-specific differential gene expression analyses based on single-cell transcriptome datasets are sensitive to the presence of cell-free mRNA in the droplets containing single cells. This so-called ambient RNA contamination may differ between samples obtained from patients and healthy control...

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Detalles Bibliográficos
Autores principales: Berg, Marijn, Petoukhov, Ilya, van den Ende, Inge, Meyer, Kerstin B., Guryev, Victor, Vonk, Judith M., Carpaij, Orestes, Banchero, Martin, Hendriks, Rudi W., van den Berge, Maarten, Nawijn, Martijn C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687889/
https://www.ncbi.nlm.nih.gov/pubmed/38030970
http://dx.doi.org/10.1186/s12864-023-09822-3

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