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TRIM45 aggravates microglia pyroptosis via Atg5/NLRP3 axis in septic encephalopathy
BACKGROUND: Neuroinflammation mediated by microglial pyroptosis is an important pathogenic mechanism of septic encephalopathy (SAE). It has been reported that TRIM45 is associated with tumours and inflammatory diseases. However, the role of TRIM45 in SAE and the relationship between TRIM45 and micro...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688018/ https://www.ncbi.nlm.nih.gov/pubmed/38037161 http://dx.doi.org/10.1186/s12974-023-02959-8 |