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TRIM45 aggravates microglia pyroptosis via Atg5/NLRP3 axis in septic encephalopathy

BACKGROUND: Neuroinflammation mediated by microglial pyroptosis is an important pathogenic mechanism of septic encephalopathy (SAE). It has been reported that TRIM45 is associated with tumours and inflammatory diseases. However, the role of TRIM45 in SAE and the relationship between TRIM45 and micro...

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Detalles Bibliográficos
Autores principales:	Huang, Xuliang, Ye, Changzhou, Zhao, Xinyu, Tong, Yao, Lin, Wen, Huang, Qingqing, Zheng, Yuhao, Wang, Junlu, Zhang, Anqi, Mo, Yunchang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688018/ https://www.ncbi.nlm.nih.gov/pubmed/38037161 http://dx.doi.org/10.1186/s12974-023-02959-8

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