Small cell neuroendocrine carcinoma with adenocarcinoma and high grade squamous intraepithelial neoplasia of the cervix

Neuroendocrine neoplasm (NEN) of the cervix is a malignant tumor and is classified into low and intermediate-grade neuroendocrine tumor (NET), and high-grade small cell neuroendocrine carcinoma (SCNEC), and large cells neuroendocrine carcinoma (LCNEC). SCNEC of the cervix is an Infrequent tumor with...

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Autores principales: Gurubalan, Guralarasan, Parwaiz, Amber, Ajit, Surabhi, Kumar, Tarun, Kumari, Madhu, Bhadani, Punam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital Universitário da Universidade de São Paulo 2023
Materias:
Clinical Case Report and Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688200/
https://www.ncbi.nlm.nih.gov/pubmed/38034519
http://dx.doi.org/10.4322/acr.2023.452
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author Gurubalan, Guralarasan
Parwaiz, Amber
Ajit, Surabhi
Kumar, Tarun
Kumari, Madhu
Bhadani, Punam
author_facet Gurubalan, Guralarasan
Parwaiz, Amber
Ajit, Surabhi
Kumar, Tarun
Kumari, Madhu
Bhadani, Punam
author_sort Gurubalan, Guralarasan
collection PubMed
description Neuroendocrine neoplasm (NEN) of the cervix is a malignant tumor and is classified into low and intermediate-grade neuroendocrine tumor (NET), and high-grade small cell neuroendocrine carcinoma (SCNEC), and large cells neuroendocrine carcinoma (LCNEC). SCNEC of the cervix is an Infrequent tumor with an incidence of less than 1% of all gynecological malignancies. It is characterized by small to medium-sized tumor cells with scant cytoplasm and neuroendocrine differentiation. Most cases of SCNEC of the cervix manifest in pure forms, and only cases show coexisting, non-neuroendocrine component of HPV-associated adenocarcinoma or squamous cell carcinoma. In this report, reviewing the literature, we present one such unique case of SCNEC of the cervix with adenocarcinoma and high-grade squamous intraepithelial neoplasia.
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spelling pubmed-106882002023-11-30 Small cell neuroendocrine carcinoma with adenocarcinoma and high grade squamous intraepithelial neoplasia of the cervix Gurubalan, Guralarasan Parwaiz, Amber Ajit, Surabhi Kumar, Tarun Kumari, Madhu Bhadani, Punam Autops Case Rep Clinical Case Report and Review Neuroendocrine neoplasm (NEN) of the cervix is a malignant tumor and is classified into low and intermediate-grade neuroendocrine tumor (NET), and high-grade small cell neuroendocrine carcinoma (SCNEC), and large cells neuroendocrine carcinoma (LCNEC). SCNEC of the cervix is an Infrequent tumor with an incidence of less than 1% of all gynecological malignancies. It is characterized by small to medium-sized tumor cells with scant cytoplasm and neuroendocrine differentiation. Most cases of SCNEC of the cervix manifest in pure forms, and only cases show coexisting, non-neuroendocrine component of HPV-associated adenocarcinoma or squamous cell carcinoma. In this report, reviewing the literature, we present one such unique case of SCNEC of the cervix with adenocarcinoma and high-grade squamous intraepithelial neoplasia. Hospital Universitário da Universidade de São Paulo 2023-11-13 /pmc/articles/PMC10688200/ /pubmed/38034519 http://dx.doi.org/10.4322/acr.2023.452 Text en Copyright © 2023 The Authors. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Case Report and Review
Gurubalan, Guralarasan
Parwaiz, Amber
Ajit, Surabhi
Kumar, Tarun
Kumari, Madhu
Bhadani, Punam
Small cell neuroendocrine carcinoma with adenocarcinoma and high grade squamous intraepithelial neoplasia of the cervix
title Small cell neuroendocrine carcinoma with adenocarcinoma and high grade squamous intraepithelial neoplasia of the cervix
title_full Small cell neuroendocrine carcinoma with adenocarcinoma and high grade squamous intraepithelial neoplasia of the cervix
title_fullStr Small cell neuroendocrine carcinoma with adenocarcinoma and high grade squamous intraepithelial neoplasia of the cervix
title_full_unstemmed Small cell neuroendocrine carcinoma with adenocarcinoma and high grade squamous intraepithelial neoplasia of the cervix
title_short Small cell neuroendocrine carcinoma with adenocarcinoma and high grade squamous intraepithelial neoplasia of the cervix
title_sort small cell neuroendocrine carcinoma with adenocarcinoma and high grade squamous intraepithelial neoplasia of the cervix
topic Clinical Case Report and Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688200/
https://www.ncbi.nlm.nih.gov/pubmed/38034519
http://dx.doi.org/10.4322/acr.2023.452
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