Cargando…

Elucidating the role of RBM5 in osteoclastogenesis: a novel potential therapeutic target for osteoporosis

Osteoporosis is a prevalent bone disease with multigene involved, and the molecular mechanisms of its pathogenesis are not entirely understood. This study aims to identify novel key genes involved in osteoporosis to discover potential pharmacological targets. We analyzed three microarray datasets an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yuyang, Chen, Xue, Xiao, Yuan, Mei, Yibo, Yang, Tong, Li, Dongchen, Wang, Xiaohui, Yang, Hao, Huang, Dageng, Hao, Dingjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688468/ https://www.ncbi.nlm.nih.gov/pubmed/38031049 http://dx.doi.org/10.1186/s12891-023-07002-8

Ejemplares similares

Percentage fat fraction in magnetic resonance imaging: upgrading the osteoporosis-detecting parameter
por: Chang, Rong, et al.
Publicado: (2020)

MicroRNAs in Osteoclastogenesis and Function: Potential Therapeutic Targets for Osteoporosis
por: Ji, Xiao, et al.
Publicado: (2016)

Proteomic profiling analysis of postmenopausal osteoporosis and osteopenia identifies potential proteins associated with low bone mineral density
por: Huang, Dageng, et al.
Publicado: (2020)

miR-21-5p targets SKP2 to reduce osteoclastogenesis in a mouse model of osteoporosis
por: Huang, Yizhen, et al.
Publicado: (2021)

α-Asarone Attenuates Osteoclastogenesis and Prevents Against Oestrogen-Deficiency Induced Osteoporosis
por: Tian, Hao, et al.
Publicado: (2022)

STAT3-mediated osteogenesis and osteoclastogenesis in osteoporosis
por: Hou, Xiaoli, et al.
Publicado: (2022)

Melatonin Inhibits Osteoclastogenesis and Osteolytic Bone Metastasis: Implications for Osteoporosis
por: MacDonald, Iona J., et al.
Publicado: (2021)

RBM6-RBM5 transcription-induced chimeras are differentially expressed in tumours
por: Wang, Ke, et al.
Publicado: (2007)

Angelica sinensis extract inhibits RANKL-mediated osteoclastogenesis by down-regulated the expression of NFATc1 in mouse bone marrow cells
por: Kong, Lingbo, et al.
Publicado: (2014)

Autoregulation of RBM10 and cross-regulation of RBM10/RBM5 via alternative splicing-coupled nonsense-mediated decay
por: Sun, Yue, et al.
Publicado: (2017)

Icaritin ameliorates RANKL-mediated osteoclastogenesis and ovariectomy-induced osteoporosis
por: Huang, Jun-ming, et al.
Publicado: (2023)

Intraoperative anti-inflammatory drugs combined with no drainage after MIS-TLIF in the treatment of recurrent lumbar disc herniation: an RCT
por: Du, Jinpeng, et al.
Publicado: (2021)

RBM24 inhibits the translation of SARS-CoV-2 polyproteins by targeting the 5ʹ-untranslated region
por: Yao, Yongxuan, et al.
Publicado: (2023)

Mediating oxidative stress through the Palbociclib/miR-141-3p/STAT4 axis in osteoporosis: a bioinformatics and experimental validation study
por: Ji, Jiajia, et al.
Publicado: (2023)

Cinnamtannin B-1 Prevents Ovariectomy-Induced Osteoporosis via Attenuating Osteoclastogenesis and ROS Generation
por: Li, Meng, et al.
Publicado: (2020)

How zoledronic acid improves osteoporosis by acting on osteoclasts
por: Wang, Biao, et al.
Publicado: (2022)

iPSC Modeling of RBM20-Deficient DCM Identifies Upregulation of RBM20 as a Therapeutic Strategy
por: Briganti, Francesca, et al.
Publicado: (2020)

Curcumin-activated Olfactory Ensheathing Cells Improve Functional Recovery After Spinal Cord Injury by Modulating Microglia Polarization Through APOE/TREM2/NF-κB Signaling Pathway
por: Jiang, Chao, et al.
Publicado: (2023)

A bacterial virulence factor interacts with the splicing factor RBM5 and stimulates formation of nuclear RBM5 granules
por: Pourpre, Renaud, et al.
Publicado: (2022)

Cryptotanshinone Suppressed Postmenopausal Osteoporosis by Preventing RANKL-Mediated Osteoclastogenesis against Kidney Injury
por: Yang, Wenjiu, et al.
Publicado: (2022)

Overexpression of RBM5 induces autophagy in human lung adenocarcinoma cells
por: Su, Zhenzhong, et al.
Publicado: (2016)

Orientin suppresses osteoclastogenesis and ameliorates ovariectomy‐induced osteoporosis via suppressing ROS production
por: Zheng, Yan, et al.
Publicado: (2023)

Matrine derivate MASM uncovers a novel function for ribosomal protein S5 in osteoclastogenesis and postmenopausal osteoporosis
por: Chen, Xiao, et al.
Publicado: (2017)

Complement receptor C5aR1 on osteoblasts regulates osteoclastogenesis in experimental postmenopausal osteoporosis
por: Bülow, Jasmin Maria, et al.
Publicado: (2022)

Vps35 loss promotes hyperresorptive osteoclastogenesis and osteoporosis via sustained RANKL signaling
por: Xia, Wen-Fang, et al.
Publicado: (2013)

Diosmetin reduces bone loss and osteoclastogenesis by regulating the expression of TRPV1 in osteoporosis rats
por: Hu, Song, et al.
Publicado: (2020)

11β-Hydroxysteroid Dehydrogenase Type 1 Facilitates Osteoporosis by Turning on Osteoclastogenesis through Hippo Signaling
por: Li, Hanwen, et al.
Publicado: (2023)

RBM10 promotes transformation-associated processes in small cell lung cancer and is directly regulated by RBM5
por: Loiselle, Julie J., et al.
Publicado: (2017)

Generation of functional dopaminergic neurons from human spermatogonial stem cells to rescue parkinsonian phenotypes
por: Yang, Hao, et al.
Publicado: (2019)

Radiological and Clinical Differences between Tinavi Orthopedic Robot and O-Arm Navigation System in Thoracolumbar Screw Implantation for Reconstruction of Spinal Stability
por: Du, Jinpeng, et al.
Publicado: (2020)

The histone methyltransferase DOT1L inhibits osteoclastogenesis and protects against osteoporosis
por: Gao, Yanpan, et al.
Publicado: (2018)

Madecassoside inhibits estrogen deficiency‐induced osteoporosis by suppressing RANKL‐induced osteoclastogenesis
por: Wang, Qingqing, et al.
Publicado: (2018)

Rbm24a and Rbm24b Are Required for Normal Somitogenesis
por: Maragh, Samantha, et al.
Publicado: (2014)

RBM14 Modulates Tubulin Acetylation and Regulates Spindle Morphology During Meiotic Maturation in Mouse Oocytes
por: Qin, Hao, et al.
Publicado: (2021)

DANCR Mediates the Rescuing Effects of Sesamin on Postmenopausal Osteoporosis Treatment via Orchestrating Osteogenesis and Osteoclastogenesis
por: Yang, Zhengmeng, et al.
Publicado: (2021)

Myrislignan targets extracellular signal-regulated kinase (ERK) and modulates mitochondrial function to dampen osteoclastogenesis and ovariectomy-induced osteoporosis
por: Yang, Tao, et al.
Publicado: (2023)

miR–483-5p promotes prostate cancer cell proliferation and invasion by targeting RBM5
por: Yang, Zhi-Gang, et al.
Publicado: (2017)

A functionalized self-assembling peptide containing E7 and YIGSR sequences enhances neuronal differentiation of spermatogonial stem cells on aligned PCL fibers for spinal cord injury repair
por: Wang, Zhiyuan, et al.
Publicado: (2022)

Gut Metabolite Urolithin A Inhibits Osteoclastogenesis and Senile Osteoporosis by Enhancing the Autophagy Capacity of Bone Marrow Macrophages
por: Tao, Huaqiang, et al.
Publicado: (2022)

Role of m6A in osteoporosis, arthritis and osteosarcoma (Review)
por: Hu, Yibo, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_kvq8evb6g4b9kr6uros2h4s5ob