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ConDoR: tumor phylogeny inference with a copy-number constrained mutation loss model

A tumor contains a diverse collection of somatic mutations that reflect its past evolutionary history and that range in scale from single nucleotide variants (SNVs) to large-scale copy-number aberrations (CNAs). However, no current single-cell DNA sequencing (scDNA-seq) technology produces accurate...

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Detalles Bibliográficos
Autores principales: Sashittal, Palash, Zhang, Haochen, Iacobuzio-Donahue, Christine A., Raphael, Benjamin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688497/
https://www.ncbi.nlm.nih.gov/pubmed/38037115
http://dx.doi.org/10.1186/s13059-023-03106-5

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