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ConDoR: tumor phylogeny inference with a copy-number constrained mutation loss model
A tumor contains a diverse collection of somatic mutations that reflect its past evolutionary history and that range in scale from single nucleotide variants (SNVs) to large-scale copy-number aberrations (CNAs). However, no current single-cell DNA sequencing (scDNA-seq) technology produces accurate...
Autores principales: | Sashittal, Palash, Zhang, Haochen, Iacobuzio-Donahue, Christine A., Raphael, Benjamin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688497/ https://www.ncbi.nlm.nih.gov/pubmed/38037115 http://dx.doi.org/10.1186/s13059-023-03106-5 |
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