Cargando…

Dynamic prediction of survival via Landmark method using the asthma prevention trial in young children

This paper focuses on the applications of Landmark method for obtaining dynamic predictions of survival by using Landmark approach to the data of asthma prevention trial in young children. This work focuses on the different ways to model recurrent events by considering various time scales according...

Descripción completa

Detalles Bibliográficos
Autores principales: Faiz, Nosheen, Gardiwal, Atal Khan, Khan, Muhammad Asif, Iftikhar, Soofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688661/
https://www.ncbi.nlm.nih.gov/pubmed/38032951
http://dx.doi.org/10.1371/journal.pone.0293796
_version_ 1785152209288167424
author Faiz, Nosheen
Gardiwal, Atal Khan
Khan, Muhammad Asif
Iftikhar, Soofia
author_facet Faiz, Nosheen
Gardiwal, Atal Khan
Khan, Muhammad Asif
Iftikhar, Soofia
author_sort Faiz, Nosheen
collection PubMed
description This paper focuses on the applications of Landmark method for obtaining dynamic predictions of survival by using Landmark approach to the data of asthma prevention trial in young children. This work focuses on the different ways to model recurrent events by considering various time scales according to how subjects in the dataset experienced multiple events. Landmark models can be used to dynamically estimate the effect of treatments effects whilst also taken into consideration the history of previous asthma attacks. Our analysis show that the treatment effect should be modelled with a time varying effect and the effect of the previous attack reduces with the passage of time.
format Online
Article
Text
id pubmed-10688661
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-106886612023-12-01 Dynamic prediction of survival via Landmark method using the asthma prevention trial in young children Faiz, Nosheen Gardiwal, Atal Khan Khan, Muhammad Asif Iftikhar, Soofia PLoS One Research Article This paper focuses on the applications of Landmark method for obtaining dynamic predictions of survival by using Landmark approach to the data of asthma prevention trial in young children. This work focuses on the different ways to model recurrent events by considering various time scales according to how subjects in the dataset experienced multiple events. Landmark models can be used to dynamically estimate the effect of treatments effects whilst also taken into consideration the history of previous asthma attacks. Our analysis show that the treatment effect should be modelled with a time varying effect and the effect of the previous attack reduces with the passage of time. Public Library of Science 2023-11-30 /pmc/articles/PMC10688661/ /pubmed/38032951 http://dx.doi.org/10.1371/journal.pone.0293796 Text en © 2023 Faiz et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Faiz, Nosheen
Gardiwal, Atal Khan
Khan, Muhammad Asif
Iftikhar, Soofia
Dynamic prediction of survival via Landmark method using the asthma prevention trial in young children
title Dynamic prediction of survival via Landmark method using the asthma prevention trial in young children
title_full Dynamic prediction of survival via Landmark method using the asthma prevention trial in young children
title_fullStr Dynamic prediction of survival via Landmark method using the asthma prevention trial in young children
title_full_unstemmed Dynamic prediction of survival via Landmark method using the asthma prevention trial in young children
title_short Dynamic prediction of survival via Landmark method using the asthma prevention trial in young children
title_sort dynamic prediction of survival via landmark method using the asthma prevention trial in young children
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688661/
https://www.ncbi.nlm.nih.gov/pubmed/38032951
http://dx.doi.org/10.1371/journal.pone.0293796
work_keys_str_mv AT faiznosheen dynamicpredictionofsurvivalvialandmarkmethodusingtheasthmapreventiontrialinyoungchildren
AT gardiwalatalkhan dynamicpredictionofsurvivalvialandmarkmethodusingtheasthmapreventiontrialinyoungchildren
AT khanmuhammadasif dynamicpredictionofsurvivalvialandmarkmethodusingtheasthmapreventiontrialinyoungchildren
AT iftikharsoofia dynamicpredictionofsurvivalvialandmarkmethodusingtheasthmapreventiontrialinyoungchildren