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Hepatocellular Brg1 promotes CCl4-induced liver inflammation, ECM accumulation and fibrosis in mice

INTRODUCTION: Hepatic fibrosis is a progressive pathological process involving the exhaustion of hepatocellular regenerative capacity and ultimately leading to the development of cirrhosis and even hepatocellular carcinoma. Brg1, the core subunit of the SWI/SNF chromatin-remodeling complex, was rece...

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Detalles Bibliográficos
Autores principales: Wang, Baocai, Kaufmann, Benedikt, Mogler, Carolin, Zhong, Suyang, Yin, Yuhan, Cheng, Zhangjun, Schmid, Roland M., Friess, Helmut, Hüser, Norbert, von Figura, Guido, Hartmann, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688683/
https://www.ncbi.nlm.nih.gov/pubmed/38033027
http://dx.doi.org/10.1371/journal.pone.0294257

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