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Substrate recognition mode of a glycoside hydrolase family 42 β-galactosidase from Bifidobacterium longum subspecies infantis (BiBga42A) revealed by crystallographic and mutational analyses
Aim: Bifidobacterium longum subsp. infantis uses a glycoside hydrolase (GH) family 42 β-galactosidase (BiBga42A) for hydrolyzing lacto-N-tetraose (LNT), which is the most abundant core structure of human milk oligosaccharides (HMOs). As such, BiBga42A represents one of the pivotal enzymes underpinni...
Autores principales: | Gotoh, Aina, Hidaka, Masafumi, Sakurama, Haruko, Nishimoto, Mamoru, Kitaoka, Motomitsu, Sakanaka, Mikiyasu, Fushinobu, Shinya, Katayama, Takane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
OAE Publishing Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688820/ https://www.ncbi.nlm.nih.gov/pubmed/38046823 http://dx.doi.org/10.20517/mrr.2023.14 |
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