Immunotherapy of cytomegalovirus infection by low-dose adoptive transfer of antiviral CD8 T cells relies on substantial post-transfer expansion of central memory cells but not effector-memory cells

Cytomegaloviruses (CMVs) are host species-specific in their replication. It is a hallmark of all CMVs that productive primary infection is controlled by concerted innate and adaptive immune responses in the immunocompetent host. As a result, the infection usually passes without overt clinical sympto...

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Detalles Bibliográficos
Autores principales: Holtappels, Rafaela, Becker, Sara, Hamdan, Sara, Freitag, Kirsten, Podlech, Jürgen, Lemmermann, Niels A., Reddehase, Matthias J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688903/
https://www.ncbi.nlm.nih.gov/pubmed/37972198
http://dx.doi.org/10.1371/journal.ppat.1011643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688903/
https://www.ncbi.nlm.nih.gov/pubmed/37972198
http://dx.doi.org/10.1371/journal.ppat.1011643

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