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Immunotherapy of cytomegalovirus infection by low-dose adoptive transfer of antiviral CD8 T cells relies on substantial post-transfer expansion of central memory cells but not effector-memory cells
Cytomegaloviruses (CMVs) are host species-specific in their replication. It is a hallmark of all CMVs that productive primary infection is controlled by concerted innate and adaptive immune responses in the immunocompetent host. As a result, the infection usually passes without overt clinical sympto...
Autores principales: | Holtappels, Rafaela, Becker, Sara, Hamdan, Sara, Freitag, Kirsten, Podlech, Jürgen, Lemmermann, Niels A., Reddehase, Matthias J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688903/ https://www.ncbi.nlm.nih.gov/pubmed/37972198 http://dx.doi.org/10.1371/journal.ppat.1011643 |
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